Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

Ga-Lai Law; Robert Pal; Lars O. Palsson; David Parker; Ka-Leung Wong

doi:10.1039/b920222f

Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

Ga-Lai Law
, Robert Pal
, Lars O. Palsson
, David Parker
, Ka-Leung Wong

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

115 Citations (Scopus)

Abstract

A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (_em 12%), allowing the creation of a ratiometric sensory system for pO₂ (versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation. © 2009 The Royal Society of Chemistry.

Original language	English
Pages (from-to)	7321-7323
Journal	Chemical Communications
Issue number	47
DOIs	https://doi.org/10.1039/b920222f
Publication status	Published - 2009
Externally published	Yes

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Funding

We thank EPSRC and the Royal Society for support.

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10.1039/b920222f

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title = "Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing",

abstract = "A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (em 12\%), allowing the creation of a ratiometric sensory system for pO2 (versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation. {\textcopyright} 2009 The Royal Society of Chemistry.",

author = "Ga-Lai Law and Robert Pal and Palsson, \{Lars O.\} and David Parker and Ka-Leung Wong",

note = "Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].",

year = "2009",

doi = "10.1039/b920222f",

language = "English",

pages = "7321--7323",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "47",

}

Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing. / Law, Ga-Lai; Pal, Robert; Palsson, Lars O. et al.
In: Chemical Communications, No. 47, 2009, p. 7321-7323.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

TY - JOUR

T1 - Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group

T2 - Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

AU - Law, Ga-Lai

AU - Pal, Robert

AU - Palsson, Lars O.

AU - Parker, David

AU - Wong, Ka-Leung

N1 - Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

PY - 2009

Y1 - 2009

N2 - A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (em 12%), allowing the creation of a ratiometric sensory system for pO2 (versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation. © 2009 The Royal Society of Chemistry.

AB - A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (em 12%), allowing the creation of a ratiometric sensory system for pO2 (versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation. © 2009 The Royal Society of Chemistry.

UR - https://www.scopus.com/pages/publications/72649102984

UR - https://www.scopus.com/pages/publications/72649102984#tab=impact

U2 - 10.1039/b920222f

DO - 10.1039/b920222f

M3 - RGC 21 - Publication in refereed journal

C2 - 20024215

SN - 1359-7345

SP - 7321

EP - 7323

JO - Chemical Communications

JF - Chemical Communications

IS - 47

ER -

Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: Applications in ratiometric oxygen sensing in vitro and in regioselective cell killing

Abstract

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