Research on imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS), Academia Sinica

Hui-Chen Tsai, Chun-Fang Chang, Bi-Chang Chen, Ji-Yen Cheng, Chih-Wei Chu, Hsieh-Cheng Han, Koji Hatanaka, Tung-Han Hsieh, Chau-Hwang Lee, Jung-Hsin Lin, Yi-Chung Tung, Pei-Kuen Wei, Fu-Liang Yang, Din Ping Tsai

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review

Abstract

Development of imaging, sensing, and characterization of cells at Research Center for Applied Sciences (RCAS) of Academia Sinica in Taiwan is progressing rapidly. The research on advanced lattice light sheet microscopy for temporal visualization of cells in three dimensions at sub-cellular resolution shows novel imaging results. Label-free observation on filopodial dynamics provides a convenient assay on cancer cell motility. The newly-developed software enables us to track the movement of two types of particles through different channels and reconstruct the co-localized tracks. Surface plasmon resonance (SPR) for detecting urinary microRNA for diagnosis of acute kidney injury demonstrates excellent sensitivity. A fully automated and integrated portable reader was constructed as a home-based surveillance system for post-operation hepatocellular carcinoma. New microfluidic cell culture devices for fast and accurate characterizations prove various diagnosis capabilities.
Original languageEnglish
Title of host publicationBiophotonics Japan 2015
PublisherSPIE
Volume9792
ISBN (Print)9781510600270
DOIs
Publication statusPublished - 2015
Externally publishedYes
EventBiophotonics Japan 2015 - Tokyo, Japan
Duration: 27 Oct 201528 Oct 2015

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9792
ISSN (Print)1605-7422

Conference

ConferenceBiophotonics Japan 2015
PlaceJapan
CityTokyo
Period27/10/1528/10/15

Bibliographical note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Research Keywords

  • Cell imaging
  • lattice light sheet microscopy
  • microfluidic cell culture devices
  • sensing technology
  • surface plasmon resonance

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