REGULATION OF SODIUM AND CALCIUM IN DAPHNIA MAGNA EXPOSED TO SILVER NANOPARTICLES

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

6 Scopus Citations
View graph of relations

Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)913-919
Journal / PublicationEnvironmental Toxicology and Chemistry
Volume32
Issue number4
Online published23 Jan 2013
Publication statusPublished - Apr 2013
Externally publishedYes

Abstract

The toxicity of manufactured silver nanoparticles (AgNPs) has been widely studied, but the influence of AgNPs on the major ions (such as sodium [Na] and calcium [Ca]) regulations are unknown. In the present study, a freshwater cladoceran Daphnia magna was exposed to commercial AgNPs coated with polyvinylpyrrolidone. After 48h, the Na body content was significantly reduced by AgNO3 exposure, but the Ca body content was significantly increased under AgNO3 and AgNP exposures, respectively. No effect was observed on the body concentrations of Na and Ca at 50 to 500 μg/L AgNPs with 1-μM cysteine addition. Exposure of AgNO3 and AgNPs inhibited the Na influx and elevated the Na efflux. In contrast, their exposure increased the Ca influx, but did not affect the Ca efflux. The results of the present study demonstrated the significant influences of AgNO3 and AgNPs (without cysteine) on Na and Ca regulations. Such effect of AgNPs on Na and Ca regulation disappeared after cysteine addition, indicating that the soluble Ag released from AgNPs played a major role in the ionoregulatory dysfunction. © 2013 SETAC.

Research Area(s)

  • Calcium, Daphnia magna, Ionoregulatory dysfunction, Silver nanoparticles, Sodium