Red blood cell extracellular vesicles as robust carriers of RNA-based therapeutics

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

4 Scopus Citations
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Detail(s)

Original languageEnglish
Pages (from-to)239-241
Journal / PublicationCell Stress
Volume2
Issue number9
Online published30 Aug 2018
Publication statusPublished - Sep 2018

Link(s)

Abstract

One of the major challenges of RNA-based therapeutics is the method for delivery of RNA molecules. In a recent article (Nat Commun 9(1):2359), we described a novel delivery platform for RNA-based drugs using red blood cell extracellular vesicles which can efficiently deliver both small and large RNAs to solid and liquid tumours. Our RBCEVs platform features exceptional merits over conventional RNA delivery methods in biosafety, biocompatibility, efficiency, accessibility, and cost effectiveness.

Research Area(s)

  • Cancer, RNA, therapeutics, extracellular vesicles, red blood cells

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