Recent advances of microneedles used towards stimuli-responsive drug delivery, disease theranostics, and bioinspired applications
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Author(s)
Related Research Unit(s)
Detail(s)
Original language | English |
---|---|
Article number | 130561 |
Journal / Publication | Chemical Engineering Journal |
Volume | 426 |
Online published | 17 Jun 2021 |
Publication status | Published - 15 Dec 2021 |
Link(s)
Abstract
Microneedles (MNs) as a minimally invasive tool have drawn increasing attention recently. They possess many prominent advantages, including pain-free, self-administration, and ease-of-disposal, when compared to the traditional administration tools. This review summarizes the latest developments of the MN technology and focuses on the advanced applications in stimuli-responsive drug delivery, disease theranostics, and bioinspired functions. Starting from a brief overview of different types of MNs based on their structures and materials, we then detail the fabrication strategies, including hot embossing, micro-molding, thermal-drawing lithography, magnetorheological lithography, laser-drilling, and the emerging 3D printing techniques. Later, the recent biomedical applications of these MNs are highlighted, including stimuli-responsive drug release for disease therapy, biosensing for disease diagnosis, and bioinspired applications.
Research Area(s)
- Microneedles, 3D printing, Stimuli-responsive, Drug delivery, Disease theranostics, Bioinspired applications
Citation Format(s)
Recent advances of microneedles used towards stimuli-responsive drug delivery, disease theranostics, and bioinspired applications. / Yang, Jingbo; Zhang, Haoxiang; Hu, Tianli; Xu, Chenjie; Jiang, Lelun; Zhang, Yu Shrike; Xie, Maobin.
In: Chemical Engineering Journal, Vol. 426, 130561, 15.12.2021.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review