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Recent advances in multifunctional magnetic nanoparticles and applications to biomedical diagnosis and treatment

  • Kai Yan
  • , Penghui Li
  • , Haie Zhu
  • , Yingjie Zhou
  • , Jingde Ding
  • , Jie Shen
  • , Zheng Li
  • , Zushun Xu
  • , Paul K. Chu

    Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

    Abstract

    By virtue of the unique magnetic properties and other functionalities, multifunctional magnetic nanoparticles (MNPs) are very promising in diagnostic and therapeutic applications. This review summarizes recent developments pertaining to the synthesis of MNPs with focus on the various surface modification strategies such as chemical synthesis, self-assembly, and ligand exchange. Recent applications of MNPs to multimodal imaging including magnetic resonance imaging (MRI)/optical imaging (fluorescent dyes, quantum dots (QDs), near-infrared absorption and up-conversion luminescence, MRI/positron emission tomography (PET), MRI/X-ray computed tomography (CT), and triple modality imaging are discussed. In addition, targeted drug and gene delivery, hyperthermia treatment for cancer, and other biomedical diagnosis rendered possible by MNPs are described. © The Royal Society of Chemistry 2013.
    Original languageEnglish
    Pages (from-to)10598-10618
    JournalRSC Advances
    Volume3
    Issue number27
    Online published25 Mar 2013
    DOIs
    Publication statusPublished - 21 Jul 2013

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

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