Rapid and room temperature detection of single nucleotide variation with enhanced discrimination by crowding assisted allele specific extension

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalNot applicablepeer-review

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Author(s)

  • Miao Cui
  • Xiaoyu Zhou
  • Xiaoyu Chen
  • Weihao Zheng
  • Liming Bian
  • And 2 others
  • Zigang Li
  • Bo Zheng

Related Research Unit(s)

Detail(s)

Original languageEnglish
Pages (from-to)12052-12055
Journal / PublicationChemical Communications
Volume55
Issue number80
Online published10 Sep 2019
Publication statusPublished - 14 Oct 2019

Abstract

In this paper we report the kinetics based detection of single nucleotide variation (SNV) at room temperature by allele specific extension with different concentrations and types of crowding agents. In general, the crowding conditions enhanced the specificity in the detection of SNV.

Citation Format(s)

Rapid and room temperature detection of single nucleotide variation with enhanced discrimination by crowding assisted allele specific extension. / Cui, Miao; Zhou, Xiaoyu; Chen, Xiaoyu; Zheng, Weihao; Bian, Liming; Li, Zigang; Zheng, Bo.

In: Chemical Communications, Vol. 55, No. 80, 14.10.2019, p. 12052-12055.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalNot applicablepeer-review