Random-access optical-resolution photoacoustic microscopy using a digital micromirror device

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Jinyang Liang
  • Yong Zhou
  • Amy W. Winkler
  • Konstantin I. Maslov
  • Chiye Li
  • Lihong V. Wang

Detail(s)

Original languageEnglish
Pages (from-to)2683-2686
Journal / PublicationOptics Letters
Volume38
Issue number15
Publication statusPublished - 1 Aug 2013
Externally publishedYes

Abstract

We developed random-access optical-resolution photoacoustic microscopy using a digital micromirror device. This system can rapidly scan arbitrarily shaped regions of interest within a 40 μm × 40 μm imaging area with a lateral resolution of 3.6 μm. To identify a region of interest, a global structural image is first acquired, then the selected region is scanned. The random-access ability was demonstrated by imaging two static samples, a carbon fiber cross and a monolayer of red blood cells, with an acquisition rate up to 4 kHz. The system was then used to monitor blood flow in vivo in real time within user-selected capillaries in a mouse ear. By imaging only the capillary of interest, the frame rate was increased by up to 9.2 times. © 2013 Optical Society of America.

Citation Format(s)

Random-access optical-resolution photoacoustic microscopy using a digital micromirror device. / Liang, Jinyang; Zhou, Yong; Winkler, Amy W. et al.
In: Optics Letters, Vol. 38, No. 15, 01.08.2013, p. 2683-2686.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review