Molecular biomimetics : Nanotechnology through biology

Research output: Journal Publications and ReviewsRGC 62 - Review of books or of software (or similar publications/items)peer-review

1476 Scopus Citations
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Author(s)

  • Mehmet Sarikaya
  • Candan Tamerler
  • Alex K.-Y. Jen
  • Klaus Schulten
  • François Baneyx

Detail(s)

Original languageEnglish
Pages (from-to)577-585
Journal / PublicationNature Materials
Volume2
Issue number9
Publication statusPublished - Sept 2003
Externally publishedYes

Abstract

Proteins, through their unique and specific interactions with other macromolecules and inorganics, control structures and functions of all biological hard and soft tissues in organisms. Molecular biomimetics is an emerging field in which hybrid technologies are developed bu using the tools of molecular biology and nanotechnology. Taking lessons from biology, polypeptides can now be genetically engineered to specifically bind to selected inorganic compounds for applications in nano- and biotechnology. This review discusses combinatorial biological protocols, that is, bacterial cell surface and phage-display technologies, in the selection of short sequences that have affinity to (noble) metals, semiconducting oxides and other technological compounds. These genetically engineered proteins for inorganics (GEPIs) can be used in the assembly of functional nanostructures. Based on the three fundamental principles of molecular recognition, self-assembly and DNA manipulation, we highlight successful uses of GEPI in nanotechnology.

Citation Format(s)

Molecular biomimetics: Nanotechnology through biology. / Sarikaya, Mehmet; Tamerler, Candan; Jen, Alex K.-Y. et al.
In: Nature Materials, Vol. 2, No. 9, 09.2003, p. 577-585.

Research output: Journal Publications and ReviewsRGC 62 - Review of books or of software (or similar publications/items)peer-review