Incidence of subclinical ketosis in cows supplemented with a monensin controlled-release capsule in Holstein cattle, Florida, USA

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • J. P. Goff
  • C. A. Risco
  • L. F. Archbald
  • R. Littell
  • G. A. Donovan

Detail(s)

Original languageEnglish
Pages (from-to)33-42
Journal / PublicationPreventive Veterinary Medicine
Volume73
Issue number1
Publication statusPublished - 16 Jan 2006
Externally publishedYes

Abstract

The objective of this study was to determine the effect of a monensin controlled-release capsule on the proportion of cows with subclinical ketosis (SK). During July to August 2001, 300 cows dried-off 50-70 days before expected parturition were randomly assigned to either a treatment (n = 150, oral capsule, 335 mg/d of monesin for 95 d) or control group (no capsule, n = 150). At 14 days postpartum, a milk sample was obtained and evaluated for β-hydroxybutyrate (BHBA) using a semi-quantitative ketone test strip. In a sub-sample of 50 cows per group a blood sample was taken and analyzed for BHBA using an ELISA kit. Milk BHBA ≥200 μmol/L was used as the cut-off value for diagnosis of SK. The incidence of SK based on the milk test was statistically different between groups (P ≤ 0.05) with a value of 26.6% for control and 14.5% for cows treated with monensin, respectively. Cows treated with monensin were 0.68 times less likely to give a positive result for milk BHBA than non-treated cows (0.53-0.80; 95% CI). Serum BHBA concentrations did not differ between groups (0.81 ± 0.09 mmol/L versus 0.70 ± 0.07 mmol/L for controls and treated, respectively; P > 0.05). However, for each incremental increase in serum BHBA of 0.1 mmol/L occurrence of SK increased 52% (OR = 1.52; 1.21-1.91; 95% CI). © 2005 Elsevier B.V. All rights reserved.

Research Area(s)

  • β-Hydroxybutyrate, Monensin, Subclinical ketosis, Transition cows

Bibliographic Note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to lbscholars@cityu.edu.hk.

Citation Format(s)

Incidence of subclinical ketosis in cows supplemented with a monensin controlled-release capsule in Holstein cattle, Florida, USA. / Melendez, P.; Goff, J. P.; Risco, C. A. et al.
In: Preventive Veterinary Medicine, Vol. 73, No. 1, 16.01.2006, p. 33-42.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review