Ultrathin MXene-Micropattern-Based Field-Effect Transistor for Probing Neural Activity

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Original languageEnglish
Pages (from-to)3333-3339
Journal / PublicationAdvanced Materials
Issue number17
Publication statusPublished - 29 Feb 2016


Researchers developed a simple and effective technique for fabricating FET transistors based on ultrathin conductive Ti3C2-MXene micropatterns, which were utilized to perform highly sensitive label-free detection of dopamine, and to monitor spiking activity in hippocampal neurons. MXene-FET biosensor was well compatible with long term neuronal culture. The transparent ultrathin layer of Ti3C2-MXene micropatterns had no interference with traditional microscpy, so that calcium imaging of neural activity could be simultaneously conducted with electrical measurement using the MXene-FET with a temporal resolution.

Research Area(s)

  • dopamine detection, field-effect transistors, micropatterning, MXenes biosensors, neural engineering