Ruthenium-indolizinone complexes as a new class of metalated heterocyclic compounds : insight into unconventional alkyne activation pathways, revelation of unexpected electronic properties and exploration of medicinal application
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
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Detail(s)
Original language | English |
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Pages (from-to) | 12838-12842 |
Journal / Publication | Dalton Transactions |
Volume | 47 |
Issue number | 37 |
Online published | 5 Jul 2018 |
Publication status | Published - 7 Oct 2018 |
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Abstract
The two series of ruthenium-indolizinone complexes prepared by Ru-mediated cyclization of pyridine-tethered alkynes represent the first examples of metalated indolizinone complexes. Joint experimental-theoretical investigation suggests an unconventional 5-endo-dig cyclization pathway as their formation mechanism. They also exhibit moderate cytotoxicity against several human cancer cell lines.
Citation Format(s)
Ruthenium-indolizinone complexes as a new class of metalated heterocyclic compounds : insight into unconventional alkyne activation pathways, revelation of unexpected electronic properties and exploration of medicinal application. / Chung, Lai-Hon; Ng, Sze-Wing; Yeung, Chi-Fung et al.
In: Dalton Transactions, Vol. 47, No. 37, 07.10.2018, p. 12838-12842.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review