Identification and expression of zebrafish Iroquois homeobox gene irx1
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Author(s)
Detail(s)
Original language | English |
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Pages (from-to) | 442-444 |
Journal / Publication | Development Genes and Evolution |
Volume | 211 |
Issue number | 8-9 |
Publication status | Published - 2001 |
Link(s)
Abstract
Iroquois homeoproteins are prepatterning factors that positively regulate proneural genes and control neurogenesis. We have identified a zebrafish Iroquois gene, irx1, which is highly homologous to Xenopus Xirol, Gallus c-Irx1 and mouse Irx1. Expression of irx1 was initially detected at the bud stage. By 16 h post-fertilization (hpf), irx1 expression was exclusively limited to the prospective midbrain and hindbrain. By 24 hpf, irx1 expression was clearly detected in the acoustic-ovestibual ganglia, tectum, tegmentum, cerebellum and rhombomere 1 but not in rhombomere 2 or mid-hind-brain boundary.
Research Area(s)
- Homeobox gene, Rhombomere, Tectum, Tegmentum, Trigeminal ganglia
Citation Format(s)
Identification and expression of zebrafish Iroquois homeobox gene irx1. / Cheng, C. W.; Hui, C. C.; Strähle, U. et al.
In: Development Genes and Evolution, Vol. 211, No. 8-9, 2001, p. 442-444.
In: Development Genes and Evolution, Vol. 211, No. 8-9, 2001, p. 442-444.
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review