Identification and expression of zebrafish Iroquois homeobox gene irx1

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

22 Scopus Citations
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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)442-444
Journal / PublicationDevelopment Genes and Evolution
Volume211
Issue number8-9
Publication statusPublished - 2001

Abstract

Iroquois homeoproteins are prepatterning factors that positively regulate proneural genes and control neurogenesis. We have identified a zebrafish Iroquois gene, irx1, which is highly homologous to Xenopus Xirol, Gallus c-Irx1 and mouse Irx1. Expression of irx1 was initially detected at the bud stage. By 16 h post-fertilization (hpf), irx1 expression was exclusively limited to the prospective midbrain and hindbrain. By 24 hpf, irx1 expression was clearly detected in the acoustic-ovestibual ganglia, tectum, tegmentum, cerebellum and rhombomere 1 but not in rhombomere 2 or mid-hind-brain boundary.

Research Area(s)

  • Homeobox gene, Rhombomere, Tectum, Tegmentum, Trigeminal ganglia

Citation Format(s)

Identification and expression of zebrafish Iroquois homeobox gene irx1. / Cheng, C. W.; Hui, C. C.; Strähle, U. et al.
In: Development Genes and Evolution, Vol. 211, No. 8-9, 2001, p. 442-444.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review