Exercise Alleviates Obesity-Induced Metabolic Dysfunction via Enhancing FGF21 Sensitivity in Adipose Tissues
Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Author(s)
Detail(s)
| Original language | English |
|---|---|
| Pages (from-to) | 2738-2752.e4 |
| Journal / Publication | Cell Reports |
| Volume | 26 |
| Issue number | 10 |
| Publication status | Published - 5 Mar 2019 |
| Externally published | Yes |
Link(s)
| DOI | DOI |
|---|---|
| Attachment(s) | Documents
Publisher's Copyright Statement
|
| Link to Scopus | https://www.scopus.com/record/display.uri?eid=2-s2.0-85061657633&origin=recordpage |
| Permanent Link | https://scholars.cityu.edu.hk/en/publications/publication(63e4f085-b085-4c92-9e42-890039ae0f4a).html |
Abstract
Geng et al. identify FGF21 signaling in adipose tissues as an obligatory molecular transducer of exercise, conferring its metabolic benefits on systemic glucose and lipid metabolism and insulin sensitivity. Exercise sensitizes FGF21 actions in adipose tissues, which in turns sends humoral signals to coordinate multi-organ crosstalk for maintaining metabolic homeostasis.
Research Area(s)
- adipokines, adipose tissue, exercise, FGF21, FGFR1, KLB, metabolic regulation, obesity, PPARγ
Bibliographic Note
Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to lbscholars@cityu.edu.hk.
Citation Format(s)
Exercise Alleviates Obesity-Induced Metabolic Dysfunction via Enhancing FGF21 Sensitivity in Adipose Tissues. / Geng, Leiluo; Liao, Boya; Jin, Leigang et al.
In: Cell Reports, Vol. 26, No. 10, 05.03.2019, p. 2738-2752.e4.Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review
Download Statistics
No data available
