Decrease in RNA folding cooperativity by deliberate population of intermediates in RNA G-quadruplexes

Chun Kit Kwok; Madeline E. Sherlock; Philip C. Bevilacqua

doi:10.1002/anie.201206475

Author(s)

Chun Kit Kwok
Madeline E. Sherlock
Philip C. Bevilacqua

Detail(s)

Original language	English
Pages (from-to)	683-686
Journal / Publication	Angewandte Chemie - International Edition
Volume	52
Issue number	2
Publication status	Published - 7 Jan 2013
Externally published	Yes

Link(s)

DOI	DOI https://doi.org/10.1002/anie.201206475 Final Published version
	Check@CityULib
Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-84871956143&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(4714ea79-1867-4182-9719-6c2e394f675a).html

Abstract

Keeping a broad (RNA) perspective: Conventional biochemical detection systems only have a 100-fold linear response range. The range of potassium concentrations detected by an RNA G-quadruplex sequence can be broadened by intentionally populating multiple intermediate folding states (see scheme). The folding of the RNA G-quadruplexes was monitored by both circular dichroism and intrinsic fluorescence spectroscopy. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Research Area(s)

fluorescence, folding cooperativity, G-quadruplexes, RNA, RNA structures

Citation Format(s)

[ RIS ] [ BibTeX ]

Decrease in RNA folding cooperativity by deliberate population of intermediates in RNA G-quadruplexes. / Kwok, Chun Kit; Sherlock, Madeline E.; Bevilacqua, Philip C.
In: Angewandte Chemie - International Edition, Vol. 52, No. 2, 07.01.2013, p. 683-686.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review

Kwok, CK, Sherlock, ME & Bevilacqua, PC 2013, 'Decrease in RNA folding cooperativity by deliberate population of intermediates in RNA G-quadruplexes', Angewandte Chemie - International Edition, vol. 52, no. 2, pp. 683-686. https://doi.org/10.1002/anie.201206475

Kwok, C. K., Sherlock, M. E., & Bevilacqua, P. C. (2013). Decrease in RNA folding cooperativity by deliberate population of intermediates in RNA G-quadruplexes. Angewandte Chemie - International Edition, 52(2), 683-686. https://doi.org/10.1002/anie.201206475

Kwok CK, Sherlock ME, Bevilacqua PC. Decrease in RNA folding cooperativity by deliberate population of intermediates in RNA G-quadruplexes. Angewandte Chemie - International Edition. 2013 Jan 7;52(2):683-686. doi: 10.1002/anie.201206475

Kwok, Chun Kit ; Sherlock, Madeline E. ; Bevilacqua, Philip C. / Decrease in RNA folding cooperativity by deliberate population of intermediates in RNA G-quadruplexes. In: Angewandte Chemie - International Edition. 2013 ; Vol. 52, No. 2. pp. 683-686.