Perfluorinated compounds and total and extractable organic fluorine in human blood samples from China

Leo W. Y. Yeung; Yuichi Miyake; Sachi Taniyasu; Yuan Wang; Hongxia Yu; M. K. So; Guibin Jiang; Yongning Wu; Jingguang Li; John P. Giesy; Nobuyoshi Yamashita; Paul K. S. Lam

doi:10.1021/es800631n

Author(s)

Leo W. Y. Yeung
Yuichi Miyake
Sachi Taniyasu
Yuan Wang
Hongxia Yu
And 7 others

M. K. So
Guibin Jiang
Yongning Wu
Jingguang Li
John P. Giesy
Nobuyoshi Yamashita
Paul K. S. Lam

Detail(s)

Original language	English
Pages (from-to)	8140-8145
Journal / Publication	Environmental Science and Technology
Volume	42
Issue number	21
Publication status	Published - 1 Nov 2008

Link(s)

DOI	DOI https://doi.org/10.1021/es800631n Final Published version
	Check@CityULib
Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-55349147982&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(3e8ccdca-3884-45d3-8768-02ac65caef1e).html

Abstract

An improved extraction (ion pairing) and cleanup (ENVI-carb and solid phase extraction) method was developed for analysis of perfluorinated compounds (PFCs) in human whole blood samples from China. Ten PFCs including PFOS, PFHxS, PFOSA, PFDoDA, PFUnDA, PFDA, PFNA, PFOA, PFHpA, and PFHxA were detected in the blood samples (n = 30) from five cities (Jintan, Nanjing, Guiyang, Beijing, and Shenyang). PFOS was found to be the dominant PFC ranging from 0.446-83.1 ng/mL. Total fluorine (TF) and extractable organic fluorine (EOF) also were measured in the blood samples using combustion ion chromatography for fluorine. Analysis of known PFCs and extractable organic fluorine showed that known PFCs could account for >70% of EOF in samples from Beijing, Shenyang, and Guiyang, whereas known PFCs could only account for ∼30% of EOF in samples from Jintan. Results of the present study indicated the presence of substantial amounts of unidentified organic fluorine in human blood samples from Jintan. Characterization and identification of these unidentified fluorinated compounds will be instructive. © 2008 American Chemical Society.

Citation Format(s)

[ RIS ] [ BibTeX ]

Perfluorinated compounds and total and extractable organic fluorine in human blood samples from China. / Yeung, Leo W. Y.; Miyake, Yuichi; Taniyasu, Sachi et al.

In: Environmental Science and Technology, Vol. 42, No. 21, 01.11.2008, p. 8140-8145.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review

Yeung, LWY, Miyake, Y, Taniyasu, S, Wang, Y, Yu, H, So, MK, Jiang, G, Wu, Y, Li, J, Giesy, JP, Yamashita, N & Lam, PKS 2008, 'Perfluorinated compounds and total and extractable organic fluorine in human blood samples from China', Environmental Science and Technology, vol. 42, no. 21, pp. 8140-8145. https://doi.org/10.1021/es800631n

Yeung, L. W. Y., Miyake, Y., Taniyasu, S., Wang, Y., Yu, H., So, M. K., Jiang, G., Wu, Y., Li, J., Giesy, J. P., Yamashita, N., & Lam, P. K. S. (2008). Perfluorinated compounds and total and extractable organic fluorine in human blood samples from China. Environmental Science and Technology, 42(21), 8140-8145. https://doi.org/10.1021/es800631n

Yeung LWY, Miyake Y, Taniyasu S, Wang Y, Yu H, So MK et al. Perfluorinated compounds and total and extractable organic fluorine in human blood samples from China. Environmental Science and Technology. 2008 Nov 1;42(21):8140-8145. doi: 10.1021/es800631n

Yeung, Leo W. Y. ; Miyake, Yuichi ; Taniyasu, Sachi et al. / Perfluorinated compounds and total and extractable organic fluorine in human blood samples from China. In: Environmental Science and Technology. 2008 ; Vol. 42, No. 21. pp. 8140-8145.