A convection-driven long-range linear gradient generator with dynamic control

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

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Author(s)

Detail(s)

Original languageEnglish
Pages (from-to)1445-1450
Journal / PublicationLab on a Chip
Volume15
Issue number6
Online published5 Jan 2015
Publication statusPublished - 21 Mar 2015
Externally publishedYes

Link(s)

DOI

DOI
Check@CityULib
Link to Scopus https://www.scopus.com/record/display.uri?eid=2-s2.0-84924256664&origin=recordpage
Permanent Link https://scholars.cityu.edu.hk/en/publications/publication(30cad7cd-b536-48dd-ad60-903d18993c47).html

Abstract

We developed a novel gradient generator to achieve long range and linear chemical gradients with a dynamic control function. The length of the gradient can be on the centimetre scale. The gradient profile can be tuned by changing the flow rates. The device can work in both high flow rate regimes with large shear stress and low flow rate regimes with minimum shear stress. The drug screening function was demonstrated by the viability test of PC-9 cancer cells.

Research Area(s)

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Publication fingerprints text

100
Convection Keyphrases
100
Dynamic Control Keyphrases
100
Shear Stress Keyphrases
100
Linear Gradient Keyphrases
100
Gradient Generator Keyphrases
100
dynamics INIS
100
control INIS
100
range INIS
100
flow rate INIS
100
convection INIS
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Citation Format(s)

[ RIS ] [ BibTeX ]
A convection-driven long-range linear gradient generator with dynamic control. / Wang, Hao; Chen, Chia-Hung; Xiang, Zhuolin et al.
In: Lab on a Chip, Vol. 15, No. 6, 21.03.2015, p. 1445-1450.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review