Ag and Ag/N2 plasma modification of polyethylene for the enhancement of antibacterial properties and cell growth/proliferation

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Wei Zhang
  • Yunjun Luo
  • Huaiyu Wang
  • Jiang Jiang
  • Shihao Pu

Detail(s)

Original languageEnglish
Pages (from-to)2028-2036
Journal / PublicationActa Biomaterialia
Volume4
Issue number6
Publication statusPublished - Nov 2008

Abstract

Polyethylene (PE) is one of the most common materials used for medical implants. However, it usually possesses low biocompatibility and insufficient antibacterial properties. In the work described here, plasma immersion ion implantation (PIII) is employed to implant silver into PE to enhance both its antibacterial properties and its biocompatibility. Our results show that Ag PIII can give rise to excellent antibacterial properties and induces the formation of functional groups such as C-O and C{double bond, long}C. These C-O and C{double bond, long}C groups on the modified surface can trigger the growth of the human fetal osteoblastic cell line (hFOB). Furthermore, combining N2 and Ag PIII prolongs the antibacterial effects, but nitrogen-containing functional groups such as C-N and C{double bond, long}N created by N2 co-PIII negatively impact proliferation of hFOB on the surface. According to our experimental investigation on cell proliferation, functional groups such as C-N and C{double bond, long}N created by nitrogen PIII are disadvantageous to cell growth whereas the C-O and C{double bond, long}C groups benefit cell growth. Both the antibacterial activity and biocompatibility of PE can be enhanced by means of the proper plasma surface treatment. © 2008 Acta Materialia Inc.

Research Area(s)

  • Antibacterial, Biocompatibility, Plasma immersion ion implantation, Polyethylene, Silver

Citation Format(s)