Single living cell refractometry using FBG-based resonant cavity

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review

3 Scopus Citations
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Author(s)

  • C. S. Lim
  • P. H. Yap
  • J. H. Ng
  • J. Z. Hao
  • S. Takahashi
  • A. Q. Liu

Detail(s)

Original languageEnglish
Title of host publicationTRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems
Pages851-854
Publication statusPublished - 2007
Externally publishedYes

Publication series

NameTRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems

Conference

Title4th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS '07
PlaceFrance
CityLyon
Period10 - 14 June 2007

Abstract

This paper reports a single cell refractometer consists of FBG fiber-based resonant cavity by employing buffer modulation method. In this biophotonic chip, single cell is trapped optically in the cavity, and the transmission spectral shifts due to the change of surrounding buffer, without and with cell, are used to determine the cell's refractive index (RI) and size. The measurement shows that MDCK cell has an effective RI of 1.383 at a precision of 0.1%. Moreover, the measurement method with optical trapping eliminates uncertain factors and prevents cell damage. The chip is promising for label-free cell measurement and further cell analysis. ©2007 IEEE.

Research Area(s)

  • Buffer modulation and refractive index, Fiber bragg gratings, Single cell measurement

Bibliographic Note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to [email protected].

Citation Format(s)

Single living cell refractometry using FBG-based resonant cavity. / Chin, L. K.; Lim, C. S.; Yap, P. H. et al.
TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems. 2007. p. 851-854 4300264 (TRANSDUCERS and EUROSENSORS '07 - 4th International Conference on Solid-State Sensors, Actuators and Microsystems).

Research output: Chapters, Conference Papers, Creative and Literary WorksRGC 32 - Refereed conference paper (with host publication)peer-review