Prospects of Nanoscience with Nanocrystals: 2025 Edition

Maria Ibáñez; Simon C. Boehme; Raffaella Buonsanti; Jonathan De Roo; Delia J. Milliron; Sandrine Ithurria; Andrey L. Rogach; Andreu Cabot; Maksym Yarema; Brandi M. Cossairt; Peter Reiss; Dmitri V. Talapin; Loredana Protesescu; Zeger Hens; Ivan Infante; Maryna I. Bodnarchuk; Xingchen Ye; Yuanyuan Wang; Hao Zhang; Emmanuel Lhuillier; Victor I. Klimov; Hendrik Utzat; Gabriele Rainò; Cherie R. Kagan; Matteo Cargnello; Jae Sung Son; Maksym V. Kovalenko

doi:10.1021/acsnano.5c07838

Prospects of Nanoscience with Nanocrystals: 2025 Edition

Maria Ibáñez^*, Simon C. Boehme, Raffaella Buonsanti, Jonathan De Roo, Delia J. Milliron, Sandrine Ithurria, Andrey L. Rogach, Andreu Cabot, Maksym Yarema, Brandi M. Cossairt, Peter Reiss, Dmitri V. Talapin, Loredana Protesescu, Zeger Hens, Ivan Infante, Maryna I. Bodnarchuk, Xingchen Ye, Yuanyuan Wang, Hao Zhang, Emmanuel LhuillierVictor I. Klimov, Hendrik Utzat, Gabriele Rainò, Cherie R. Kagan, Matteo Cargnello, Jae Sung Son, Maksym V. Kovalenko^*

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

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Abstract

Nanocrystals (NCs) of various compositions have made important contributions to science and technology, with their impact recognized by the 2023 Nobel Prize in Chemistry for the discovery and synthesis of semiconductor quantum dots (QDs). Over four decades of research into NCs has led to numerous advancements in diverse fields, such as optoelectronics, catalysis, energy, medicine, and recently, quantum information and computing. The last 10 years since the predecessor perspective “Prospect of Nanoscience with Nanocrystals” was published in ACS Nano have seen NC research continuously evolve, yielding critical advances in fundamental understanding and practical applications. Mechanistic insights into NC formation have translated into precision control over NC size, shape, and composition. Emerging synthesis techniques have broadened the landscape of compounds obtainable in colloidal NC form. Sophistication in surface chemistry, jointly bolstered by theoretical models and experimental findings, has facilitated refined control over NC properties and represents a trusted gateway to enhanced NC stability and processability. The assembly of NCs into superlattices, along with two-dimensional (2D) photolithography and three-dimensional (3D) printing, has expanded their utility in creating materials with tailored properties. Applications of NCs are also flourishing, consolidating progress in fields targeted early on, such as optoelectronics and catalysis, and extending into areas ranging from quantum technology to phase-change memories. In this perspective, we review the extensive progress in research on NCs over the past decade and highlight key areas where future research may bring further breakthroughs. © 2025 The Authors. Published by American Chemical Society

Original language	English
Pages (from-to)	31969-32051
Number of pages	83
Journal	ACS Nano
Volume	19
Issue number	36
Online published	3 Sept 2025
DOIs	https://doi.org/10.1021/acsnano.5c07838
Publication status	Published - 16 Sept 2025

Funding

This article was inspired by the discussions and presentations at the NaNaX10 ( Nanoscience with Nanocrystals) conference held in the Institute of Science and Technology of Austria (ISTA), July 3\u20137, 2023. M.I. acknowledges financial support from the Werner Siemens Foundation (WSS) and Abayomi Lawal, Christine Fiedler, Ihor Cherniukh, Francesco Milillo, Navita Jakhar, and Magali Lorion for all their help in editing this manuscript. M.I. would also like to acknowledge Christine Fiedler for the design of the TOC. S.C.B. acknowledges Dr. Dmitry Dirin for proofreading and the Weizmann-ETH Zurich Bridge Program for financial support. A.C. thanks Linlin Yang for drafting Figure 6 and acknowledges support from the project Sydecat with reference PID2022-136883OB-C22 under MCIN/AEI/10.13039/501100011033/FEDER, UE, and to the Departament de Recerca i Universitats of the Generalitat de Catalunya (2021 SGR 01581). M.C. acknowledges support from the Sloan Foundation, BASF Corporation, the Novo Nordisk Foundation CO Research Center (CORC), and the US Department of Energy, Chemical Sciences, Geosciences and Biosciences Division of the Office of Basic Energy Sciences, via the SUNCAT Center for Interface Science and Catalysis. D.V.T. acknowledges support from the U.S. National Science Foundation under Grant Number CHE-2404291. V.I.K. acknowledges support by the Solar Photochemistry Program of the Chemical Sciences, Biosciences and Geosciences Division, Office of Basic Energy Sciences, Office of Science, U.S. Department of Energy (overview of studies of spin-exchange interactions in Mn-doped QDs) and the Laboratory Directed Research and Development (LDRD) program at Los Alamos National Laboratory under project 20250443ER (overview of QD optical gain and lasing studies). E.L. acknowledges financial from the ERC grant blackQD (grant no. 756225) and AQDtive (grant no. 101086358), and from French state funds managed by the ANR through the grants Bright (ANR-21-CE24-0012-02), MixDferro (ANR-21-CE09-0029), Quicktera (ANR-22-CE09-0018), E-map (ANR-23-CE50-0025), DIRAC (ANR-24-ASM1-0001), camIR (ANR-24-CE42-2757), and Piquant (ANR-24-CE09-0786). L.P. acknowledges financial support from SOLAR NL, funded by the National Growth Fund in The Netherlands. G.R. acknowledges funding from the Swiss National Science Foundation (Grant No. 200021_192308, \u201CQ-Light\u2500Engineered Quantum Light Sources with Nanocrystal Assemblies\u201D). P.R. acknowledges funding from European Union\u2019s Horizon research and innovation program under grant agreement 101135704 (HortiQD project) and from the French Research Agency ANR (grant ANR-24-CE09-0786-01 PIQUANT). A.L.R. acknowledges financial support from the Innovation and Technology Commission of Hong Kong (ITS/027/22MX), and from the Research Grant Council of Hong Kong SAR through the RGC Senior Research Fellow Scheme (SRFS 2324-1S04). J.S.S. acknowledges financial support from the National Research Foundation of Korea (NRF) grant funded by the Ministry of Science and ICT (2022R1A2C3009129). X.Y. acknowledges support from the U.S. National Science Foundation under awards DMR-2102526 and CBET-2223453. Y.W. acknowledges the support from the Science and Technology Program in Jiangsu Province (BK20232041) and the National Natural Science Foundation of China (22171132 and 52472165). M.Y. acknowledges funding by the European Research Council (ERC) under the European Union\u2019s Horizon 2020 research and innovation programme, grant agreement No. 852751. I.I., Z.H. and M.K acknowledge the European Commission for funding (MSCA-DN Track The Twin, grant agreement 101168820). Z.H. acknowledges funding from the FWO-Vlaanderen (research projects G0B2921N and G0C5723N) and Ghent University (BOF-GOA 01G02124). H.Z. acknowledges W. Liu for editing Figure 19 and the financial support from Beijing Natural Science Foundation (JQ24003). 2

Research Keywords

assembly
catalysis
fluorescence
hard ceramics
high-entropy alloy
lasing
nanocrystal
optoelectronics
perovskites
photolithography
photonics
quantum dot
quantum light
semiconductor
surface chemistry
synthesis
thermoelectrics

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Ibáñez, M., Boehme, S. C., Buonsanti, R., De Roo, J., Milliron, D. J., Ithurria, S., Rogach, A. L., Cabot, A., Yarema, M., Cossairt, B. M., Reiss, P., Talapin, D. V., Protesescu, L., Hens, Z., Infante, I., Bodnarchuk, M. I., Ye, X., Wang, Y., Zhang, H., ... Kovalenko, M. V. (2025). Prospects of Nanoscience with Nanocrystals: 2025 Edition. ACS Nano, 19(36), 31969-32051. https://doi.org/10.1021/acsnano.5c07838

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abstract = "Nanocrystals (NCs) of various compositions have made important contributions to science and technology, with their impact recognized by the 2023 Nobel Prize in Chemistry for the discovery and synthesis of semiconductor quantum dots (QDs). Over four decades of research into NCs has led to numerous advancements in diverse fields, such as optoelectronics, catalysis, energy, medicine, and recently, quantum information and computing. The last 10 years since the predecessor perspective “Prospect of Nanoscience with Nanocrystals” was published in ACS Nano have seen NC research continuously evolve, yielding critical advances in fundamental understanding and practical applications. Mechanistic insights into NC formation have translated into precision control over NC size, shape, and composition. Emerging synthesis techniques have broadened the landscape of compounds obtainable in colloidal NC form. Sophistication in surface chemistry, jointly bolstered by theoretical models and experimental findings, has facilitated refined control over NC properties and represents a trusted gateway to enhanced NC stability and processability. The assembly of NCs into superlattices, along with two-dimensional (2D) photolithography and three-dimensional (3D) printing, has expanded their utility in creating materials with tailored properties. Applications of NCs are also flourishing, consolidating progress in fields targeted early on, such as optoelectronics and catalysis, and extending into areas ranging from quantum technology to phase-change memories. In this perspective, we review the extensive progress in research on NCs over the past decade and highlight key areas where future research may bring further breakthroughs. {\textcopyright} 2025 The Authors. Published by American Chemical Society",

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Ibáñez, M, Boehme, SC, Buonsanti, R, De Roo, J, Milliron, DJ, Ithurria, S, Rogach, AL, Cabot, A, Yarema, M, Cossairt, BM, Reiss, P, Talapin, DV, Protesescu, L, Hens, Z, Infante, I, Bodnarchuk, MI, Ye, X, Wang, Y, Zhang, H, Lhuillier, E, Klimov, VI, Utzat, H, Rainò, G, Kagan, CR, Cargnello, M, Son, JS & Kovalenko, MV 2025, 'Prospects of Nanoscience with Nanocrystals: 2025 Edition', ACS Nano, vol. 19, no. 36, pp. 31969-32051. https://doi.org/10.1021/acsnano.5c07838

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AU - Rogach, Andrey L.

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AU - Yarema, Maksym

AU - Cossairt, Brandi M.

AU - Reiss, Peter

AU - Talapin, Dmitri V.

AU - Protesescu, Loredana

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AU - Bodnarchuk, Maryna I.

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AU - Zhang, Hao

AU - Lhuillier, Emmanuel

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AB - Nanocrystals (NCs) of various compositions have made important contributions to science and technology, with their impact recognized by the 2023 Nobel Prize in Chemistry for the discovery and synthesis of semiconductor quantum dots (QDs). Over four decades of research into NCs has led to numerous advancements in diverse fields, such as optoelectronics, catalysis, energy, medicine, and recently, quantum information and computing. The last 10 years since the predecessor perspective “Prospect of Nanoscience with Nanocrystals” was published in ACS Nano have seen NC research continuously evolve, yielding critical advances in fundamental understanding and practical applications. Mechanistic insights into NC formation have translated into precision control over NC size, shape, and composition. Emerging synthesis techniques have broadened the landscape of compounds obtainable in colloidal NC form. Sophistication in surface chemistry, jointly bolstered by theoretical models and experimental findings, has facilitated refined control over NC properties and represents a trusted gateway to enhanced NC stability and processability. The assembly of NCs into superlattices, along with two-dimensional (2D) photolithography and three-dimensional (3D) printing, has expanded their utility in creating materials with tailored properties. Applications of NCs are also flourishing, consolidating progress in fields targeted early on, such as optoelectronics and catalysis, and extending into areas ranging from quantum technology to phase-change memories. In this perspective, we review the extensive progress in research on NCs over the past decade and highlight key areas where future research may bring further breakthroughs. © 2025 The Authors. Published by American Chemical Society

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Prospects of Nanoscience with Nanocrystals: 2025 Edition

Abstract

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Research Keywords

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SRFS: Plasmonically Enhanced Mid-infrared Narrow-bandgap Semiconductor Nanocrystals Towards Practical Optoelectronic Applications

ITF-ExtU-Lead: Dual-modality Optical/Chemical Gas Sensing Technologies for air Pollution Monitoring

Cite this

Prospects of Nanoscience with Nanocrystals: 2025 Edition

Abstract

Funding

Research Keywords

Publisher's Copyright Statement

RGC Funding Information

Access Output

Other Access Options

Permanent Link

Other Files and Links

Fingerprint

Projects

SRFS: Plasmonically Enhanced Mid-infrared Narrow-bandgap Semiconductor Nanocrystals Towards Practical Optoelectronic Applications

ITF-ExtU-Lead: Dual-modality Optical/Chemical Gas Sensing Technologies for air Pollution Monitoring

Cite this