Promoting active health with AI technologies: Current status and prospects of high-altitude therapy, simulated hypoxia, and LLM-driven lifestyle rehabilitation approaches

Mingyu Liu, Wenli Zhang*, Junyu Wang, Kehan Bao, Ziyi Fu, Boyuan Wang*

*Corresponding author for this work

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

Abstract

In the context of the rising global prevalence of obesity, traditional intervention measures have proven insufficient to meet the demands of personalized and sustainable health management, necessitating the exploration of innovative solutions through innovative technologies. This study explores how advanced digital technologies, including Internet of Things (IoT) and Artificial Intelligence (AI), can manage weight and enhance full-lifecycle health in individuals with obesity under simulated high-altitude hypoxic conditions (HC). The findings suggest that integrating simulated HC with digital health technologies offers a novel and safe approach to obesity rehabilitation. By leveraging environmental stimuli, real-time monitoring through wearable devices, and intelligent evaluation using large language models (LLMs), this method enables more scientific weight loss, prevents rebound weight gain, and fosters proactive healthy lifestyles, significantly improving weight control outcomes for individuals with obesity. Future research should evaluate the efficacy of simulated HC in weight management and its long-term impact on obesity control. Establishing an integrated framework that combines simulated HC, lifestyle interventions, and smart health ecosystems is crucial for advancing rehabilitative healthcare and addressing the global burden of obesity through digital innovation.
Original languageEnglish
Pages (from-to)252-265
JournalBioScience Trends
Volume19
Issue number3
Online published29 Apr 2025
DOIs
Publication statusPublished - Jun 2025

Funding

This research was funded by the National Key R&D Program 'Prevention and Treatment Research for Cancer, Cardiovascular, Respiratory, and Metabolic Diseases' under the Science and Technology Innovation 2030 initiative, Project 'Key Technology and Intervention Strategy Research for Plateau Holistic Health Security Based on Multi-center Population Cohorts', grant number 2023ZD0505300/2023ZD0505303 and Medical Scientific Research Foundation of Guangdong Province of China, grant number A2023159.

Research Keywords

  • personalized weight management
  • digital health innovation
  • lifestyle intervention
  • obesity rehabilitation
  • sustainable health improvement
  • public health management
  • plateau innovation industry

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