Promising Ta-Ti-Zr-Si metallic glass coating without cytotoxic elements for bio-implant applications

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalNot applicablepeer-review

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Author(s)

  • J.J. Lai
  • Y.S. Lin
  • C.H. Chang
  • T.Y. Wei
  • Z.X. Liao
  • C.H. Lin
  • C.H. Chen

Related Research Unit(s)

Detail(s)

Original languageEnglish
Pages (from-to)485-495
Journal / PublicationApplied Surface Science
Volume427
Issue numberPart A
StatePublished - 1 Jan 2018

Abstract

Tantalum (Ta) is considered as one of the most promising metal due to its high corrosion resistance, excellent biocompatibility and cell adhesion/in-growth capabilities. Although there are some researches exploring the biomedical aspects of Ta and Ta based alloys, systematic characterizations of newly developed Ta-based metallic glasses in bio-implant applications is still lacking. This study employs sputtering approach to produced thin-film Ti-based metallic glasses due to the high melting temperature of Ta (3020C). Two fully amorphous Ta-based metallic glasses composed of Ta57Ti17Zr15Si11 and Ta75Ti10Zr8Siare produced and experimentally characterized in terms of their mechanical properties, bio-corrosion properties, surface hydrophilic characteristics, and in-vitro cell viability and cells attachment tests. Compare to conventional pure Ti and Ta metals, the developed Ta-based metallic glasses exhibit higher hardness and lower modulus which are better match to the mechanical properties of bone. MTS assay results show that Ta-based metallic glasses show comparable cell viability and cell attachment rate compared to that of pure Ti and Ta surface in a 72 h in-vitro test.

Research Area(s)

  • Biocompatibility, Cell viability, Cells attachment, Ta-based metallic glass

Citation Format(s)

Promising Ta-Ti-Zr-Si metallic glass coating without cytotoxic elements for bio-implant applications. / Lai, J.J.; Lin, Y.S.; Chang, C.H.; Wei, T.Y.; Huang, J.C.; Liao, Z.X.; Lin, C.H.; Chen, C.H.

In: Applied Surface Science, Vol. 427, No. Part A, 01.01.2018, p. 485-495.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalNot applicablepeer-review