Promising antimicrobial capability of thin film metallic glasses

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Y.Y. Chu
  • Y.S. Lin
  • C.M. Chang
  • J.-K. Liu
  • C.H. Chen

Detail(s)

Original languageEnglish
Pages (from-to)221-225
Journal / PublicationMaterials Science and Engineering C
Volume36
Online published15 Dec 2013
Publication statusPublished - 1 Mar 2014
Externally publishedYes

Abstract

Thin film metallic glasses (TFMGs) are demonstrated to exhibit excellent surface flatness, high corrosion resistance and satisfactory hydrophobic properties. Moreover, the antimicrobial and biocompatibility abilities of TFMGs are examined and the results are compared with the behavior of pure Ag and 316 L stainless steel. Three TFMGs, Al48Ag37Ti15, Zr54Ti35Si11, and Zr59Ti 22Ag19, are prepared by sputtering to assess the antimicrobial performance against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa, which are the most common nosocomial infection pathogens. Experimental results show that the antimicrobial effect of the Al- or Ag-containing AlAgTi and ZrTiAg TFMGs is similar to that of the pure Ag coating. The ZrTiSi TFMG with no Ag or Al shows poor antimicrobial capability. The physical properties of highly smooth surface and hydrophobic nature alone are not sufficient to result in promising antimicrobial ability. The chemical metal ion release still plays a major role, which should be born in mind in designing biomedical devices.

Research Area(s)

  • Antimicrobial effect, Metallic glass, Silver, Thin film

Citation Format(s)

Promising antimicrobial capability of thin film metallic glasses. / Chu, Y.Y.; Lin, Y.S.; Chang, C.M. et al.
In: Materials Science and Engineering C, Vol. 36, 01.03.2014, p. 221-225.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review