Prodrug Strategies for Paclitaxel
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Author(s)
Detail(s)
| Original language | English |
|---|---|
| Article number | 796 |
| Journal / Publication | International Journal of Molecular Sciences |
| Volume | 17 |
| Issue number | 5 |
| Online published | 23 May 2016 |
| Publication status | Published - 2016 |
| Externally published | Yes |
Link(s)
| DOI | DOI |
|---|---|
| Attachment(s) | Documents
Publisher's Copyright Statement
|
| Link to Scopus | https://www.scopus.com/record/display.uri?eid=2-s2.0-84969677939&origin=recordpage |
| Permanent Link | https://scholars.cityu.edu.hk/en/publications/publication(5247baa5-63a1-48dc-b70a-6e3f21f61b0a).html |
Abstract
Paclitaxel is an anti-tumor agent with remarkable anti-tumor activity and wide clinical uses. However, it is also faced with various challenges especially for its poor water solubility and low selectivity for the target. To overcome these disadvantages of paclitaxel, approaches using small molecule modifications and macromolecule modifications have been developed by many research groups from all over the world. In this review, we discuss the different strategies especially prodrug strategies that are currently used to make paclitaxel more effective.
Research Area(s)
- paclitaxel, poor water solubility, low selectivity, prodrug
Citation Format(s)
Prodrug Strategies for Paclitaxel. / Meng, Ziyuan; Lv, Quanxia; Lu, Jun et al.
In: International Journal of Molecular Sciences, Vol. 17, No. 5, 796, 2016.
In: International Journal of Molecular Sciences, Vol. 17, No. 5, 796, 2016.
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
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