Preparation of unsymmetrical distyryl BODIPY derivatives and effects of the styryl substituents on their in vitro photodynamic properties

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Hui He
  • Pui-Chi Lo
  • Sin-Lui Yeung
  • Wing-Ping Fong
  • Dennis K. P. Ng

Detail(s)

Original languageEnglish
Pages (from-to)4748-4750
Journal / PublicationChemical Communications
Volume47
Issue number16
Publication statusPublished - 28 Apr 2011
Externally publishedYes

Abstract

A series of unsymmetrical distyryl BODIPYs have been prepared which function as highly potent photosensitisers with in vitro IC50 values as low as 15 nM. Their cellular uptake, subcellular localisation and photocytotoxicity depend greatly on the styryl substituents. © The Royal Society of Chemistry 2011.

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