Preferential incorporation of trans, trans-conjugated linoleic acid isomers into the liver of suckling rats

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Lin Yang
  • Sai Ying Venus Yeung
  • Yu Huang
  • Han Qing Wang
  • Zhen-Yu Chen

Detail(s)

Original languageEnglish
Pages (from-to)253-260
Journal / PublicationBritish Journal of Nutrition
Volume87
Issue number3
Publication statusPublished - 2002
Externally publishedYes

Abstract

The present study was designed to compare the conjugated linoleic acid (CLA) isomeric distribution pattern in the liver of suckling rats in relation to those in the milk and maternal diet. Silver-ion HPLC was used to separate individual CLA isomers. It was found that the isomeric distribution pattern in the milk was very similar to that in the maternal dietary fat. However, the CLA isomeric distribution patterns in the liver phospholipids (PL) and triacylglycerols were different from those in the diet and milk. In the liver PL, total cis/trans isomers accounted for 63.6-63.9 % of total CLA, which was in contrast to the values of 88.1-89.1 % in the milk and diet. In the liver PL, total trans/trans isomers were 20.6-20.8 % of the total CLA isomers whereas they were only 2.6-3.7 % in the milk and diet. It is concluded that trans/trans-CLA were preferentially incorporated into the liver whereas for the incorporation of cis/trans-CLA there was partial discrimination.

Research Area(s)

  • Conjugated linoleic acids, Milk, Neonate, Phospholipids, Triacylglycerols

Bibliographic Note

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Citation Format(s)

Preferential incorporation of trans, trans-conjugated linoleic acid isomers into the liver of suckling rats. / Yang, Lin; Yeung, Sai Ying Venus; Huang, Yu; Wang, Han Qing; Chen, Zhen-Yu.

In: British Journal of Nutrition, Vol. 87, No. 3, 2002, p. 253-260.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review