Portable molecularly imprinted polymer-based platform for detection of histamine in aqueous solutions

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Chi-Chung Yeung
  • Tan Li
  • Siu Chuen Lau
  • Ling-Yi Li
  • Jin Hua Li

Detail(s)

Original languageEnglish
Article number124609
Journal / PublicationJournal of Hazardous Materials
Volume410
Online published21 Nov 2020
Publication statusPublished - 15 May 2021

Abstract

Histamine, which is a naturally occurring chemical in seafood, is known to cause undesirable inflammatory response when consumed in large amounts. Histamine is produced in unsafe amounts in colored seafood when improperly stored for just a few hours. Food and health regulatory bodies across the world have guidelines limiting the amount of histamine in fresh as well as processed seafood. Conventional histamine detection is performed in testing labs, which is a slow process and results in bottlenecks in the seafood supply-chain system. A system to rapidly detect the seafood histamine levels on site is very desirable for seafood suppliers. Herein, we describe an impedance-based histamine detection sensor built on a flexible substrate that can detect histamine in the range of 100–500 ppm. Moreover, our sensor discriminates histamine in the presence of DL-histidine and other biogenic amines, with the selectivity provided by molecular imprinting technology. As a proof of concept, a smartphone controlled, portable semi-quantitative histamine sensing device was fabricated that gave out reliable testing results for histamine in different test solutions as well as for real seafood. We believe this technology can be extended towards determination of other food contaminants in aqueous solutions.

Research Area(s)

  • Flexible histamine sensor, Portable smartphone-based sensor, Seafood contamination

Citation Format(s)

Portable molecularly imprinted polymer-based platform for detection of histamine in aqueous solutions. / Venkatesh, Shishir; Yeung, Chi-Chung; Li, Tan; Lau, Siu Chuen; Sun, Qi-Jun; Li, Ling-Yi; Li, Jin Hua; Lam, Michael H.W.; Roy, Vellaisamy A.L.

In: Journal of Hazardous Materials, Vol. 410, 124609, 15.05.2021.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review