Plasmonic metallic nanoparticle-based biosensors
Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review
Author(s)
Related Research Unit(s)
Detail(s)
Original language | English |
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Title of host publication | Enhanced Spectroscopies and Nanoimaging 2023 |
Editors | Prabhat Verma, Yung Doug Suh |
Publisher | SPIE |
ISBN (electronic) | 9781510665231 |
ISBN (print) | 9781510665224 |
Publication status | Published - 2023 |
Publication series
Name | Proceedings of SPIE - The International Society for Optical Engineering |
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Volume | 12654 |
ISSN (Print) | 0277-786X |
ISSN (electronic) | 1996-756X |
Conference
Title | Enhanced Spectroscopies and Nanoimaging 2023 |
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Place | United States |
City | San Diego |
Period | 20 - 23 August 2023 |
Link(s)
Abstract
Bifunctional nanoparticle of combining magnetic and plasmonic nanomaterials retain both unique properties, contributing to the high photothermal performance, excellent biocompatibility, physiological stability, low cytotoxicity and easy separation. Herein, we report a core-shell plasmonic magnetic nanostructure (PMNs), then introduce the plasmonic photothermal polymerase chain reaction (PPT-PCR) platform for fast, sensitive, cheap, and simple nucleic acid detection based on PMNs. Magnetic nanoparticles can be synthesized by solvothermal reaction. PMNs can be prepared after Au coating on the magnetic core, which can act as nanoheater and heat solution to 95 ℃ in several seconds upon infra-red (IR) light irradiation, and can be collected by magnet easily. Furthermore, our platforms utilize ultrafast PCR amplification based on the photothermal effect of plasmonic magnetic nanoparticles for molecular diagnostics through two modes, including in-situ end-point quantitative fluorescence detection (PPT-qPCR) and colorimetric assay (PPT-cPCR), having comparable limit of detection (LOD) on DNA targets. © 2023 SPIE.
Research Area(s)
- bifunctional nanoparticle, biosensor, colorimetric, photothermal effect, Plasmonic magnetic nanoparticle, plasmonic PCR, polymerase chain reaction
Bibliographic Note
Full text of this publication does not contain sufficient affiliation information. With consent from the author(s) concerned, the Research Unit(s) information for this record is based on the existing academic department affiliation of the author(s).
Citation Format(s)
Plasmonic metallic nanoparticle-based biosensors. / Lee, Jung-hoon; Mi, Hua.
Enhanced Spectroscopies and Nanoimaging 2023. ed. / Prabhat Verma; Yung Doug Suh. SPIE, 2023. 126540B (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 12654).
Enhanced Spectroscopies and Nanoimaging 2023. ed. / Prabhat Verma; Yung Doug Suh. SPIE, 2023. 126540B (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 12654).
Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review