Photoresponsive spherical nucleic acid : spatiotemporal control of the assembly circuit and intracellular microRNA release

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

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Author(s)

  • Xiang Zhou
  • Miao He
  • Xue Yin
  • Dongbao Yao
  • Shiyan Xiao
  • Haojun Liang

Detail(s)

Original languageEnglish
Pages (from-to)106-109
Journal / PublicationChemical Communications (London)
Volume54
Issue number1
Publication statusPublished - 4 Jan 2018

Link(s)

DOI

DOI
Check@CityULib
Link to Scopus https://www.scopus.com/record/display.uri?eid=2-s2.0-85038616775&origin=recordpage
Permanent Link https://scholars.cityu.edu.hk/en/publications/publication(fa7dac99-d528-4d35-b729-b5f63d225057).html

Abstract

Herein, we designed and prepared a photoresponsive spherical nucleic acid (SNA) conjugate by inserting a photocleavable linker into the recognition sequence of SNA which can block the reactivity of the system temporally until specific UV light (∼365 nm) is introduced. The photoresponsive SNA realizes temporal regulation of a self-assembly reaction circuit and spatial selectivity of microRNA release in a cell population, respectively.

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Publication fingerprints text

100
Photoresponsivity Keyphrases
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MicroRNA Keyphrases
100
Spatiotemporal Cont... Keyphrases
100
Spherical nucleic A... Keyphrases
100
Nucleic Acid Chemistry
100
control INIS
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nucleic acids INIS
100
Acid Chemical Engineering
25
UV Light Keyphrases
25
Cell Population Keyphrases
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Citation Format(s)

[ RIS ] [ BibTeX ]
Photoresponsive spherical nucleic acid: spatiotemporal control of the assembly circuit and intracellular microRNA release. / Zhou, Xiang; Li, Hui; He, Miao et al.
In: Chemical Communications (London), Vol. 54, No. 1, 04.01.2018, p. 106-109.

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review