Photonic Quantum Computing for RNA Structure and Gene Regulation

Kin Tung Michael Ho, Yuk Lung Lawrence Ho, Shang Yu, Kin Lai Michelle Ho, Ronghan Zhang, Zexuan Wang, Giin Yu Amy Tan, Po-Heng Lee*

*Corresponding author for this work

Research output: Conference PapersRGC 32 - Refereed conference paper (without host publication)peer-review

Abstract

Ribonucleic acids (RNA) play a crucial role in the post-transcriptional regulation of gene expression in cellular metabolic processes. However, analysing their structures and interactions, which are often represented as graph-based problems, poses complex, computationally intensive challenges. Gaussian Boson Sampling (GBS), a photonic quantum computational technique, offers a promising solution beyond the capabilities of classical algorithms. This work investigates the applications of GBS in RNA folding prediction and multi-omics analysis, specifically across transcriptomic and proteomic levels, to address structural and functional relationships in gene regulation. Additionally, we discuss current hardware limitations and future directions for advancing the technology. By bridging quantum computing and molecular biology, this interdisciplinary approach provides transformative opportunities for both fields.
Original languageEnglish
Publication statusPublished - 25 Jun 2025
Event2025 IEEE International Conference on Quantum Control, Computing, and Learning (IEEE qCCL 2025) - The Hong Kong Polytechnic University, Hong Kong, Hong Kong, China
Duration: 25 Jun 202528 Jun 2025
https://events.polyu.edu.hk/IEEE_qCCL2025/home

Conference

Conference2025 IEEE International Conference on Quantum Control, Computing, and Learning (IEEE qCCL 2025)
PlaceHong Kong, China
CityHong Kong
Period25/06/2528/06/25
Internet address

Bibliographical note

Research Unit(s) information for this publication is provided by the author(s) concerned.

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