Photofunctional Transition Metal Complexes as Intracellular Sensors, Cytotoxic Agents, and Bioorthogonal Probes

Research output: Conference PapersRGC 31B - Invited conference paper (non-refereed items)Yes

Abstract

The coordination of functional ligands to d-block elements results in transition metal complexes with new and useful properties. We are particularly interested in the photophysical and photochemical characteristics of luminescent transition metal polypyridine complexes since they offer new opportunities for the development of innovative diagnostic and therapeutic reagents. In this presentation, we will describe our recent designs of luminescent rhenium(I), ruthenium(II), and iridium(III) polypyridine complexes as intracellular molecular sensors, photocytotoxic agents, and phosphorogenic bioorthogonal probes for specific staining of live cells. We will focus on the photophysical and photochemical properties, cytotoxic activity, cellular uptake behavior, and intracellular functions of these photofunctional transition metal complexes.
Original languageEnglish
Publication statusPublished - 30 Jul 2018
Event43rd International Conference on Coordination Chemistry (ICCC2018) - Sendai, Japan
Duration: 30 Jul 20184 Aug 2018
http://www.iccc2018.jp/

Conference

Conference43rd International Conference on Coordination Chemistry (ICCC2018)
PlaceJapan
CitySendai
Period30/07/184/08/18
Internet address

Bibliographical note

Information for this record is supplemented by the author(s) concerned.

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