Photofunctional cyclometallated iridium(III) polypyridine methylsulfone complexes as sulfhydryl-specific reagents for bioconjugation, bioimaging and photocytotoxic applications

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Detail(s)

Original languageEnglish
Article number10162
Journal / PublicationChemical Communications
Volume58
Issue number73
Online published8 Aug 2022
Publication statusPublished - 18 Sep 2022

Abstract

We report herein near-infrared (NIR)-emitting cyclometallated iridium(III) complexes bearing a heteroaromatic methylsulfone moiety as sulfhydryl-specific reagents; one of the complexes was conjugated to cysteine and cysteine-containing peptides and proteins for bioimaging and photocytotoxic applications.

Research Area(s)

  • LABELING REAGENTS, LUMINESCENT, CONJUGATION, PEPTIDES, PROTEINS, RECEPTOR

Citation Format(s)

Photofunctional cyclometallated iridium(III) polypyridine methylsulfone complexes as sulfhydryl-specific reagents for bioconjugation, bioimaging and photocytotoxic applications. / Huang, Lili; Leung, Peter Kam-Keung; Lee, Lawrence Cho-Cheung et al.

In: Chemical Communications, Vol. 58, No. 73, 10162, 18.09.2022.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review