Photofunctional cyclometallated iridium(III) polypyridine methylsulfone complexes as sulfhydryl-specific reagents for bioconjugation, bioimaging and photocytotoxic applications

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Detail(s)

Original languageEnglish
Pages (from-to)10162-10165
Journal / PublicationChemical Communications
Volume58
Issue number73
Online published8 Aug 2022
Publication statusPublished - 18 Sept 2022

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Abstract

We report herein near-infrared (NIR)-emitting cyclometallated iridium(III) complexes bearing a heteroaromatic methylsulfone moiety as sulfhydryl-specific reagents; one of the complexes was conjugated to cysteine and cysteine-containing peptides and proteins for bioimaging and photocytotoxic applications.

Research Area(s)

  • LABELING REAGENTS, LUMINESCENT, CONJUGATION, PEPTIDES, PROTEINS, RECEPTOR

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