TY - JOUR
T1 - Photoactivatable cytotoxic agents derived from mitochondria-targeting luminescent iridium(III) poly(ethylene glycol) complexes modified with a nitrobenzyl linkage
AU - Tso, Karson Ka-Shun
AU - Leung, Kam-Keung
AU - Liu, Hua-Wei
AU - Lo, Kenneth Kam-Wing
PY - 2016/3/25
Y1 - 2016/3/25
N2 - Two novel photoactivatable mitochondria-targeting luminescent iridium(iii) poly(ethylene glycol) (PEG) complexes incorporated with a nitrobenzyl group were designed. They showed minimal cytotoxic activity in the dark, but became significantly cytotoxic upon irradiation due to the release of the PEG pendants.
AB - Two novel photoactivatable mitochondria-targeting luminescent iridium(iii) poly(ethylene glycol) (PEG) complexes incorporated with a nitrobenzyl group were designed. They showed minimal cytotoxic activity in the dark, but became significantly cytotoxic upon irradiation due to the release of the PEG pendants.
UR - http://www.scopus.com/inward/record.url?scp=84961267125&partnerID=8YFLogxK
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-84961267125&origin=recordpage
U2 - 10.1039/c6cc00918b
DO - 10.1039/c6cc00918b
M3 - RGC 21 - Publication in refereed journal
SN - 0009-241X
VL - 52
SP - 4557
EP - 4560
JO - Chemical Communications
JF - Chemical Communications
IS - 24
ER -