PhageScope : a well-annotated bacteriophage database with automatic analyses and visualizations

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

25 Scopus Citations
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Detail(s)

Original languageEnglish
Pages (from-to)D756–D761
Journal / PublicationNucleic acids research
Volume52
Issue numberD1
Online published30 Oct 2023
Publication statusPublished - 5 Jan 2024

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Abstract

Bacteriophages are viruses that infect bacteria or archaea. Understanding the diverse and intricate genomic architectures of phages is essential to study microbial ecosystems and develop phage therapy strategies. However, the existing phage databases are short of meticulous annotations. To this end, we propose PhageScope (https://phagescope.deepomics.org), an online phage database with comprehensive annotations. PhageScope harbors a collection of 873 718 phage sequences from various sources. Applying fifteen state-of-the-art tools to perform systematic annotations and analyses, PhageScope provides annotations on genome completeness, host range, lifestyle information, taxonomy classification, nine types of structural and functional genetic elements, and three types of comparative genomic studies for curated phages. Additionally, PhageScope incorporates automatic analyses and visualizations for curated and customized phages, serving as an efficient platform for phage study. © The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

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