Peptide microarray for high-throughput determination of phosphatase specificity and biology

Hongyan Sun; Candy H. S. Lu; Mahesh Uttamchandani; Yun Xia; Yih-Cherng Liou; Shao Q. Yao

doi:10.1002/anie.200703473

Author(s)

Candy H. S. Lu
Mahesh Uttamchandani
Yun Xia
Yih-Cherng Liou
Shao Q. Yao

Detail(s)

Original language	English
Pages (from-to)	1698-1702
Journal / Publication	Angewandte Chemie - International Edition
Volume	47
Issue number	9
Publication status	Published - 15 Feb 2008
Externally published	Yes

Link(s)

DOI	DOI https://doi.org/10.1002/anie.200703473 Final Published version
	Check@CityULib
Link to Scopus	https://www.scopus.com/record/display.uri?eid=2-s2.0-41049117046&origin=recordpage
Permanent Link	https://scholars.cityu.edu.hk/en/publications/publication(80b8a718-1df4-4f6e-9e96-83b9538f14ec).html

Abstract

Identifying phosphatase substrates: A peptide microarray has been developed for the high-throughput study of Ser/Thr phosphatases. Putative peptide substrates, upon immobilization onto a glass slide, could be used to obtain kinetic information and identify the substrate preferences of a Ser/Thr phosphatase (see schematic representation); with this information, new biology of the enzyme could be discovered. (Figure Presented) © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

Research Area(s)

Microarrays, Peptides, Phosphatases, Phosphorylation, Substrate specificity

Citation Format(s)

[ RIS ] [ BibTeX ]

Peptide microarray for high-throughput determination of phosphatase specificity and biology. / Sun, Hongyan; Lu, Candy H. S.; Uttamchandani, Mahesh et al.

In: Angewandte Chemie - International Edition, Vol. 47, No. 9, 15.02.2008, p. 1698-1702.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62) › 21_Publication in refereed journal › peer-review

Sun, H, Lu, CHS, Uttamchandani, M, Xia, Y, Liou, Y-C & Yao, SQ 2008, 'Peptide microarray for high-throughput determination of phosphatase specificity and biology', Angewandte Chemie - International Edition, vol. 47, no. 9, pp. 1698-1702. https://doi.org/10.1002/anie.200703473

Sun, H., Lu, C. H. S., Uttamchandani, M., Xia, Y., Liou, Y-C., & Yao, S. Q. (2008). Peptide microarray for high-throughput determination of phosphatase specificity and biology. Angewandte Chemie - International Edition, 47(9), 1698-1702. https://doi.org/10.1002/anie.200703473

Sun H, Lu CHS, Uttamchandani M, Xia Y, Liou Y-C, Yao SQ. Peptide microarray for high-throughput determination of phosphatase specificity and biology. Angewandte Chemie - International Edition. 2008 Feb 15;47(9):1698-1702. doi: 10.1002/anie.200703473

Sun, Hongyan ; Lu, Candy H. S. ; Uttamchandani, Mahesh et al. / Peptide microarray for high-throughput determination of phosphatase specificity and biology. In: Angewandte Chemie - International Edition. 2008 ; Vol. 47, No. 9. pp. 1698-1702.