Palladium-based kinetic resolution of racemic tosylaziridines

Wa-Hung Leung; Wing-Leung Mak; Eddie Y. Y. Chan; Tony C. H. Lam; Wing-Sze Lee; Hoi-Lun Kwong; Lam-Lung Yeung

doi:10.1055/s-2002-34221

Palladium-based kinetic resolution of racemic tosylaziridines

Wa-Hung Leung, Wing-Leung Mak, Eddie Y. Y. Chan, Tony C. H. Lam, Wing-Sze Lee, Hoi-Lun Kwong, Lam-Lung Yeung

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

17 Citations (Scopus)

Abstract

Dicationic Pd(II) complexes with chiral pyridine bis(oxazoline) ligands are catalysts for kinetic resolution of racemic styrene tosylazirdines, Treatment of styrene tosylaziridine with 0.5 equivalents of alcohol in the presence of the chiral Pd catalyst affords β-alkoxy tosylamide with ee up to 71%.

Original language	English
Pages (from-to)	1688-1690
Journal	Synlett
Issue number	10
DOIs	https://doi.org/10.1055/s-2002-34221
Publication status	Published - 2002

Research Keywords

Alcoholysis
Asymmetric
Aziridine
Kinetic resolution
Palladium

Access Output

10.1055/s-2002-34221

Other Access Options

Check CityUHK Library

Permanent Link

Right click to copy link

Cite this

@article{48cdb11a69b4414aa7e5ac301e6594db,

title = "Palladium-based kinetic resolution of racemic tosylaziridines",

abstract = "Dicationic Pd(II) complexes with chiral pyridine bis(oxazoline) ligands are catalysts for kinetic resolution of racemic styrene tosylazirdines, Treatment of styrene tosylaziridine with 0.5 equivalents of alcohol in the presence of the chiral Pd catalyst affords β-alkoxy tosylamide with ee up to 71%.",

keywords = "Alcoholysis, Asymmetric, Aziridine, Kinetic resolution, Palladium",

author = "Wa-Hung Leung and Wing-Leung Mak and Chan, {Eddie Y. Y.} and Lam, {Tony C. H.} and Wing-Sze Lee and Hoi-Lun Kwong and Lam-Lung Yeung",

year = "2002",

doi = "10.1055/s-2002-34221",

language = "English",

pages = "1688--1690",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "10",

}

TY - JOUR

T1 - Palladium-based kinetic resolution of racemic tosylaziridines

AU - Leung, Wa-Hung

AU - Mak, Wing-Leung

AU - Chan, Eddie Y. Y.

AU - Lam, Tony C. H.

AU - Lee, Wing-Sze

AU - Kwong, Hoi-Lun

AU - Yeung, Lam-Lung

PY - 2002

Y1 - 2002

N2 - Dicationic Pd(II) complexes with chiral pyridine bis(oxazoline) ligands are catalysts for kinetic resolution of racemic styrene tosylazirdines, Treatment of styrene tosylaziridine with 0.5 equivalents of alcohol in the presence of the chiral Pd catalyst affords β-alkoxy tosylamide with ee up to 71%.

AB - Dicationic Pd(II) complexes with chiral pyridine bis(oxazoline) ligands are catalysts for kinetic resolution of racemic styrene tosylazirdines, Treatment of styrene tosylaziridine with 0.5 equivalents of alcohol in the presence of the chiral Pd catalyst affords β-alkoxy tosylamide with ee up to 71%.

KW - Alcoholysis

KW - Asymmetric

KW - Aziridine

KW - Kinetic resolution

KW - Palladium

UR - http://www.scopus.com/inward/record.url?scp=0036401538&partnerID=8YFLogxK

UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-0036401538&origin=recordpage

U2 - 10.1055/s-2002-34221

DO - 10.1055/s-2002-34221

M3 - RGC 21 - Publication in refereed journal

SN - 0936-5214

SP - 1688

EP - 1690

JO - Synlett

JF - Synlett

IS - 10

ER -

Palladium-based kinetic resolution of racemic tosylaziridines

Abstract

Research Keywords

Access Output

Other Access Options

Permanent Link

Other Files and Links

Fingerprint

Cite this