Oxygen Detection of Single Cells with Guided Movements

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review

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Detail(s)

Original languageEnglish
Title of host publication2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)
PublisherInstitute of Electrical and Electronics Engineers, Inc.
Pages963-966
Number of pages4
ISBN (electronic)9784886864352
ISBN (print)979-8-3503-3302-2
Publication statusPublished - Jun 2023

Publication series

NameInternational Conference on Solid-State Sensors, Actuators and Microsystems, Transducers
ISSN (Print)2167-0013
ISSN (electronic)2167-0021

Conference

Title22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2023)
LocationKyoto International Conference Center
PlaceJapan
CityKyoto
Period25 - 29 June 2023

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Link to Scopus https://www.scopus.com/record/display.uri?eid=2-s2.0-85193505931&origin=recordpage
Permanent Link https://scholars.cityu.edu.hk/en/publications/publication(47df1d7a-cbb9-413f-8a43-7ac294751f90).html

Abstract

Measurement of oxygen (O2) consumption is a critical parameter for understanding cell behaviors and viability in many biological systems. In this study, an O2 detection platform that comprises a luminescent dye-based optical O2 sensor and guiding structures was presented. This platform was employed to investigate the relationship between the O2 consumption of single cells and cell movements. Real-time observation of changes in O2 consumption was achieved as single cells were guided by patterned structures using the proposed O2 detection platform. The results demonstrate that changes in O2 consumption were associated with the area of mitochondria within the cell. Specifically, O2 consumption increased as the area occupied by mitochondria increased, as evidenced by an increase in the fluorescence intensity of the optical O2 sensor. These findings lay the foundation for studying cell activities and viability in tissue engineering. © 2023 IEEJ.

Research Area(s)

  • Oxygen Detection, Optical Oxygen Sensor, Guided Movements, MC3T3-E1 Cell

Bibliographic Note

Information for this record is supplemented by the author(s) concerned.

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Publication fingerprints text

100
detection INIS
100
oxygen INIS
100
Oxygen Detection Keyphrases
100
O2 Consumption Keyphrases
100
Guided Motion Keyphrases
100
Mitochondrion Material Science
100
Detection Engineering
66
Sensor Engineering
50
Fluorescence Material Science
40
Cell Viability Keyphrases
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Citation Format(s)

[ RIS ] [ BibTeX ]
Oxygen Detection of Single Cells with Guided Movements. / Wang, Muting; Pang, Stella W.
2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers). Institute of Electrical and Electronics Engineers, Inc., 2023. p. 963-966 (International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers).

Research output: Chapters, Conference Papers, Creative and Literary Works › RGC 32 - Refereed conference paper (with host publication) › peer-review