Osmium(vi) complexes as a new class of potential anti-cancer agents

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Wen-Xiu Ni
  • Wai-Lun Man
  • Myra Ting-Wai Cheung
  • Raymond Wai-Yin Sun
  • Yuan-Lan Shu
  • Chi-Ming Che

Detail(s)

Original languageEnglish
Pages (from-to)2140-2142
Journal / PublicationChemical Communications
Volume47
Issue number7
Publication statusPublished - 21 Feb 2011

Abstract

A nitridoosmium(vi) complex [OsVI(N)(sap)(OH2)Cl] (H2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5′-guanosine monophosphate. © 2011 The Royal Society of Chemistry.

Citation Format(s)

Osmium(vi) complexes as a new class of potential anti-cancer agents. / Ni, Wen-Xiu; Man, Wai-Lun; Cheung, Myra Ting-Wai; Sun, Raymond Wai-Yin; Shu, Yuan-Lan; Lam, Yun-Wah; Che, Chi-Ming; Lau, Tai-Chu.

In: Chemical Communications, Vol. 47, No. 7, 21.02.2011, p. 2140-2142.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review