Oscillation and its inhibition in a neuronal network model for tinnitus sound therapy.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)22_Publication in policy or professional journal

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Author(s)

  • Hirofumi Nagashino
  • Ken'ichi Fujimoto
  • Yohsuke Kinouchi
  • Ali A Danesh
  • Abhijit S Pandya

Detail(s)

Original languageEnglish
Pages (from-to)311-314
Journal / PublicationConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
Publication statusPublished - 2008
Externally publishedYes

Abstract

Tinnitus is the perception of phantom sounds in the ears or in the head. Sound therapy techniques for tinnitus treatment have been proposed. In order to investigate mechanisms of tinnitus generation and the clinical effects of sound therapy from the viewpoint of neural engineering, we have proposed a computational model using a neural oscillator. In the present paper, we propose another model that is composed of model neurons described by simplified Hodgkin-Huxley equations. By computer simulation it was detected that this model also has a bistable state, i.e., a stable oscillatory state and a stable equilibrium (non-oscillatory) state coexist at a certain parameter region. It was also noticed that the oscillation can be inhibited by supplying constant or pulse train stimuli, which is hypothesized as an afferent signal that is employed as an acoustical signal for tinnitus treatment. By hypothesizing that the oscillation and the equilibrium correspond to generation and inhibition of tinnitus, respectively, these phenomena could explain the fact that the habituated human auditory system temporarily halts perception of tinnitus following sound therapy.

Citation Format(s)

Oscillation and its inhibition in a neuronal network model for tinnitus sound therapy. / Nagashino, Hirofumi; Fujimoto, Ken'ichi; Kinouchi, Yohsuke; Danesh, Ali A; Pandya, Abhijit S; He, Jufang.

In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2008, p. 311-314.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)22_Publication in policy or professional journal