Ordered-standing nickel hydroxide microchannel arrays: Synthesis and application for highly sensitive non-enzymatic glucose sensors

Fengjuan Miao; Bairui Tao; Paul K. Chu

doi:10.1016/j.mee.2014.11.005

Ordered-standing nickel hydroxide microchannel arrays: Synthesis and application for highly sensitive non-enzymatic glucose sensors

Fengjuan Miao, Bairui Tao^*, Paul K. Chu

^*Corresponding author for this work

Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review

9 Citations (Scopus)

Abstract

A non-enzymatic glucose sensor is constructed by using nickel hydroxide (Ni(OH)₂) modified silicon microchannel plates (MCP) as the sensing materials. The 3D ordered Si MCP is fabricated by electrochemical etching and the Ni(OH)₂ coating are prepared by electroless plating. The nanocomposite electrode exhibits good catalytic activity toward oxidation of glucose in 0.1 M KOH. This non-enzymatic glucose sensor boasts a fast amperometric response time of less than 5 s, sensitivity of 0.25 mA mM^-1 cm^-2, and detection limit of 3.5 μM at a signal-to-noise ratio of 3. The sensor shows superior stability, anti-interference capability, and selectivity. The good analytical capability, low cost, and compatibility with silicon technology make the Ni(OH)₂/Si MCP electrode promising in amperometric non-enzymatic glucose detection.

Original language	English
Pages (from-to)	11-15
Journal	Microelectronic Engineering
Volume	133
DOIs	https://doi.org/10.1016/j.mee.2014.11.005
Publication status	Published - 3 Aug 2015

Research Keywords

Electrochemical sensor
Glucose oxidase
Nickel hydroxide
Ordered channels

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title = "Ordered-standing nickel hydroxide microchannel arrays: Synthesis and application for highly sensitive non-enzymatic glucose sensors",

abstract = "A non-enzymatic glucose sensor is constructed by using nickel hydroxide (Ni(OH)2) modified silicon microchannel plates (MCP) as the sensing materials. The 3D ordered Si MCP is fabricated by electrochemical etching and the Ni(OH)2 coating are prepared by electroless plating. The nanocomposite electrode exhibits good catalytic activity toward oxidation of glucose in 0.1 M KOH. This non-enzymatic glucose sensor boasts a fast amperometric response time of less than 5 s, sensitivity of 0.25 mA mM-1 cm-2, and detection limit of 3.5 μM at a signal-to-noise ratio of 3. The sensor shows superior stability, anti-interference capability, and selectivity. The good analytical capability, low cost, and compatibility with silicon technology make the Ni(OH)2/Si MCP electrode promising in amperometric non-enzymatic glucose detection.",

keywords = "Electrochemical sensor, Glucose oxidase, Nickel hydroxide, Ordered channels",

author = "Fengjuan Miao and Bairui Tao and Chu, {Paul K.}",

year = "2015",

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doi = "10.1016/j.mee.2014.11.005",

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journal = "Microelectronic Engineering",

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T2 - Synthesis and application for highly sensitive non-enzymatic glucose sensors

AU - Miao, Fengjuan

AU - Tao, Bairui

AU - Chu, Paul K.

PY - 2015/8/3

Y1 - 2015/8/3

N2 - A non-enzymatic glucose sensor is constructed by using nickel hydroxide (Ni(OH)2) modified silicon microchannel plates (MCP) as the sensing materials. The 3D ordered Si MCP is fabricated by electrochemical etching and the Ni(OH)2 coating are prepared by electroless plating. The nanocomposite electrode exhibits good catalytic activity toward oxidation of glucose in 0.1 M KOH. This non-enzymatic glucose sensor boasts a fast amperometric response time of less than 5 s, sensitivity of 0.25 mA mM-1 cm-2, and detection limit of 3.5 μM at a signal-to-noise ratio of 3. The sensor shows superior stability, anti-interference capability, and selectivity. The good analytical capability, low cost, and compatibility with silicon technology make the Ni(OH)2/Si MCP electrode promising in amperometric non-enzymatic glucose detection.

AB - A non-enzymatic glucose sensor is constructed by using nickel hydroxide (Ni(OH)2) modified silicon microchannel plates (MCP) as the sensing materials. The 3D ordered Si MCP is fabricated by electrochemical etching and the Ni(OH)2 coating are prepared by electroless plating. The nanocomposite electrode exhibits good catalytic activity toward oxidation of glucose in 0.1 M KOH. This non-enzymatic glucose sensor boasts a fast amperometric response time of less than 5 s, sensitivity of 0.25 mA mM-1 cm-2, and detection limit of 3.5 μM at a signal-to-noise ratio of 3. The sensor shows superior stability, anti-interference capability, and selectivity. The good analytical capability, low cost, and compatibility with silicon technology make the Ni(OH)2/Si MCP electrode promising in amperometric non-enzymatic glucose detection.

KW - Electrochemical sensor

KW - Glucose oxidase

KW - Nickel hydroxide

KW - Ordered channels

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DO - 10.1016/j.mee.2014.11.005

M3 - RGC 21 - Publication in refereed journal

SN - 0167-9317

VL - 133

SP - 11

EP - 15

JO - Microelectronic Engineering

JF - Microelectronic Engineering

ER -

Ordered-standing nickel hydroxide microchannel arrays: Synthesis and application for highly sensitive non-enzymatic glucose sensors

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