Optofluidic detection for cellular phenotyping
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review
Author(s)
Detail(s)
Original language | English |
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Pages (from-to) | 3552-3565 |
Journal / Publication | Lab on a Chip - Miniaturisation for Chemistry and Biology |
Volume | 12 |
Issue number | 19 |
Publication status | Published - 7 Oct 2012 |
Link(s)
Abstract
Quantitative analysis of the output of processes and molecular interactions within a single cell is highly critical to the advancement of accurate disease screening and personalized medicine. Optical detection is one of the most broadly adapted measurement methods in biological and clinical assays and serves cellular phenotyping. Recently, microfluidics has obtained increasing attention due to several advantages, such as small sample and reagent volumes, very high throughput, and accurate flow control in the spatial and temporal domains. Optofluidics, which is the attempt to integrate optics with microfluidics, shows great promise to enable on-chip phenotypic measurements with high precision, sensitivity, specificity, and simplicity. This paper reviews the most recent developments of optofluidic technologies for cellular phenotyping optical detection. © The Royal Society of Chemistry.
Citation Format(s)
Optofluidic detection for cellular phenotyping. / Tung, Yi-Chung; Huang, Nien-Tsu; Oh, Bo-Ram et al.
In: Lab on a Chip - Miniaturisation for Chemistry and Biology, Vol. 12, No. 19, 07.10.2012, p. 3552-3565.
In: Lab on a Chip - Miniaturisation for Chemistry and Biology, Vol. 12, No. 19, 07.10.2012, p. 3552-3565.
Research output: Journal Publications and Reviews › RGC 21 - Publication in refereed journal › peer-review