Optofluidic detection for cellular phenotyping

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Yi-Chung Tung
  • Nien-Tsu Huang
  • Bo-Ram Oh
  • Bishnubrata Patra
  • Chi-Chun Pan
  • Teng Qiu
  • Wenjun Zhang
  • Katsuo Kurabayashi

Detail(s)

Original languageEnglish
Pages (from-to)3552-3565
Journal / PublicationLab on a Chip - Miniaturisation for Chemistry and Biology
Volume12
Issue number19
Publication statusPublished - 7 Oct 2012

Abstract

Quantitative analysis of the output of processes and molecular interactions within a single cell is highly critical to the advancement of accurate disease screening and personalized medicine. Optical detection is one of the most broadly adapted measurement methods in biological and clinical assays and serves cellular phenotyping. Recently, microfluidics has obtained increasing attention due to several advantages, such as small sample and reagent volumes, very high throughput, and accurate flow control in the spatial and temporal domains. Optofluidics, which is the attempt to integrate optics with microfluidics, shows great promise to enable on-chip phenotypic measurements with high precision, sensitivity, specificity, and simplicity. This paper reviews the most recent developments of optofluidic technologies for cellular phenotyping optical detection. © The Royal Society of Chemistry.

Citation Format(s)

Optofluidic detection for cellular phenotyping. / Tung, Yi-Chung; Huang, Nien-Tsu; Oh, Bo-Ram et al.
In: Lab on a Chip - Miniaturisation for Chemistry and Biology, Vol. 12, No. 19, 07.10.2012, p. 3552-3565.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review