TY - JOUR
T1 - Optimizing tomato waste hydrolysate for enhanced fucoxanthin biosynthesis in mixotrophic cultivation of Isochrysis galbana
AU - Fan, Xi-Wen
AU - Sun, Han
AU - Ayittey, Derek M.
AU - Zhou, Zhi-gang
AU - Sze Ki Lin, Carol
AU - Tang, Tao
AU - Sun, Zheng
PY - 2024/12
Y1 - 2024/12
N2 - Vegetable waste, rich in bioactive compounds, offers a promising resource for producing value-added products. This study explored the use of tomato waste, containing glucose (40 mg/g), lycopene (95.12 μg/g), and β-carotene (24.31 μg/g), for cultivating fucoxanthin-rich Isochrysis galbana. Water-soluble lycopene (2.0 μg/mL) and β-carotene (0.4 μg/mL) effectively upregulated key carotenoid synthesis genes and boosted cell growth and fucoxanthin production (3.64 and 3.60 pg/cell, respectively) within 10 days in a mixotrophic culture. Optimized tomato waste hydrolysate achieved a high cell density of 1.21 × 107 cells/mL, 2.13 g/L biomass, and 21.02 mg/g fucoxanthin. This study highlights the potential of combining tomato waste with microalgae for a novel and innovative approach towards waste management and resource utilization. © 2024 Elsevier Ltd.
AB - Vegetable waste, rich in bioactive compounds, offers a promising resource for producing value-added products. This study explored the use of tomato waste, containing glucose (40 mg/g), lycopene (95.12 μg/g), and β-carotene (24.31 μg/g), for cultivating fucoxanthin-rich Isochrysis galbana. Water-soluble lycopene (2.0 μg/mL) and β-carotene (0.4 μg/mL) effectively upregulated key carotenoid synthesis genes and boosted cell growth and fucoxanthin production (3.64 and 3.60 pg/cell, respectively) within 10 days in a mixotrophic culture. Optimized tomato waste hydrolysate achieved a high cell density of 1.21 × 107 cells/mL, 2.13 g/L biomass, and 21.02 mg/g fucoxanthin. This study highlights the potential of combining tomato waste with microalgae for a novel and innovative approach towards waste management and resource utilization. © 2024 Elsevier Ltd.
KW - Algal Bioproducts
KW - Carotenoid biosynthesis
KW - Lycopene
KW - Waste valorization
KW - β-carotene
UR - http://www.scopus.com/inward/record.url?scp=85203852479&partnerID=8YFLogxK
UR - https://www.scopus.com/record/pubmetrics.uri?eid=2-s2.0-85203852479&origin=recordpage
U2 - 10.1016/j.biortech.2024.131453
DO - 10.1016/j.biortech.2024.131453
M3 - RGC 21 - Publication in refereed journal
C2 - 39251032
SN - 0960-8524
VL - 413
JO - Bioresource Technology
JF - Bioresource Technology
M1 - 131453
ER -
