Optical sensing of biomolecules using microring resonators

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Ayça Yalçin
  • Ketul C. Popat
  • John C. Aldridge
  • Tejal A. Desai
  • John Hryniewicz
  • Nabil Chbouki
  • Brent E. Little
  • Oliver King
  • Vien Van
  • David Gill
  • Matthew Anthes-Washburn
  • M. Selim Ünlü
  • Bennett B. Goldberg

Detail(s)

Original languageEnglish
Pages (from-to)148-154
Journal / PublicationIEEE Journal on Selected Topics in Quantum Electronics
Volume12
Issue number1
Publication statusPublished - Jan 2006
Externally publishedYes

Abstract

A biosensor application of vertically coupled glass microring resonators with Q ∼ 12 000 is introduced. Using balanced photodetection, very high signal to noise ratios, and thus high sensitivity to refractive index changes (limit of detection of 1.8 × 10-5 refractive index units), are achieved. Ellipsometry and X-ray photoelectron spectroscopy results indicate successful modification of biosensor surfaces. Experimental data obtained separately for a bulk change of refractive index of the medium and for avidin-biotin binding on the ring surface are reported. Excellent repeatability and close-to-complete surface regeneration after binding are experimentally demonstrated. 

Research Area(s)

  • Biomedical transducer, Cavity resonator, Circular waveguide

Citation Format(s)

Optical sensing of biomolecules using microring resonators. / Yalçin, Ayça; Popat, Ketul C.; Aldridge, John C.; Desai, Tejal A.; Hryniewicz, John; Chbouki, Nabil; Little, Brent E.; King, Oliver; Van, Vien; Chu, Sai; Gill, David; Anthes-Washburn, Matthew; Ünlü, M. Selim; Goldberg, Bennett B.

In: IEEE Journal on Selected Topics in Quantum Electronics, Vol. 12, No. 1, 01.2006, p. 148-154.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review