Optical and biological sensing capabilities of Au2S/AuAgS coated gold nanorods

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal

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Author(s)

  • Haowen Huang
  • Xuanyong Liu
  • Yunlong Zeng
  • Xianyong Yu
  • Bo Liao
  • Pinggui Yi

Detail(s)

Original languageEnglish
Pages (from-to)5622-5630
Journal / PublicationBiomaterials
Volume30
Issue number29
Publication statusPublished - Oct 2009

Abstract

Gold nanorods coated with a multiplex component, namely Au2S/AuAgS coated gold nanorods, are produced without precipitation and aggregation among the nanorods. Both the thickness of the shell and size of the core can be readily controlled by this technique allowing one to tune the plasmon resonance of the nanocomposites over a range of several hundred nanometers. These Au2S/AuAgS coated gold nanorods exhibit interesting optical properties and are suitable for many biological sensing applications. Functionalization of the Au2S/AuAgS coated gold nanorods is achieved by manipulating the affinity between the Au2S/AuAgS and thiol compounds. Biomolecules can be covalently attached via the NH2 bond of the antibodies to the NHS-terminated nanorods. The longitudinal peaks of the Au2S/AuAgS coated gold nanorods are extremely sensitive to the refractive index changes induced by target binding, suggesting that they are excellent sensors for target-specific binding events and have the potential to achieve single-molecule sensitivity in microspectroscopy. © 2009 Elsevier Ltd. All rights reserved.

Research Area(s)

  • Au2S/AuAgS coated gold nanorods Core-shell nanostructure Optical properties, Biological sensing, Functionalization, Nanorods

Citation Format(s)

Optical and biological sensing capabilities of Au2S/AuAgS coated gold nanorods. / Huang, Haowen; Liu, Xuanyong; Zeng, Yunlong; Yu, Xianyong; Liao, Bo; Yi, Pinggui; Chu, Paul K.

In: Biomaterials, Vol. 30, No. 29, 10.2009, p. 5622-5630.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journal