Occurrence of anthelmintic resistant equine cyathostome populations in central and southern Italy

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Donato Traversa
  • Thomas R. Klei
  • Raffaella Iorio
  • Barbara Paoletti
  • Riccardo P. Lia
  • Domenico Otranto
  • Annunziata Giangaspero

Detail(s)

Original languageEnglish
Pages (from-to)314-320
Journal / PublicationPreventive Veterinary Medicine
Volume82
Issue number3-4
Online published14 Dec 2007
Publication statusPublished - 14 Dec 2007
Externally publishedYes

Abstract

In the present survey, 276 horses bred on 16 farms located in central and southern Italy were investigated for the presence of drug resistant cyathostomes by a Fecal Egg Count Reduction Test (FECRT). Sixteen to 20 animals were selected on each farm and randomly assigned to one of four equally sized treatment groups. Groups were treated with fenbendazole, pyrantel pamoate, ivermectin or moxidectin. Resistance to fenbendazole was declared on six farms (37.5%) and suspected in two farms (12.5%), with FECR values ranging from 41% to 88.3%. Resistance to pyrantel was found in two farms (12.5%) and was suspected in one case (6.2%), with FECR values ranging from 43% to 85.4%. Macrocyclic lactones remained effective on all farms. Only cyathostome third stage larvae (L3) were found in fecal cultures after treatment. This paper reports the first wide survey conducted in Italy for anthelmintic resistance in equine cyathostomes. The results indicate that multiple drug resistant equine cyathostomes are present in the central and southern regions of Italy. These data call for a geographically and numerically broader investigation of horse farms in all regions and for the development and implementation -among veterinarians, owners and managers of a plan to reduce the expansion of these anthelmintic resistant populations and control these important parasites.

Research Area(s)

  • Anthelmintic resistance, Cyathostomes, FECRT, Fenbendazole, Horse, Italy, Ivermectin, Moxidectin, Nematoda, Pyrantel pamoate

Citation Format(s)

Occurrence of anthelmintic resistant equine cyathostome populations in central and southern Italy. / Traversa, Donato; Klei, Thomas R.; Iorio, Raffaella et al.
In: Preventive Veterinary Medicine, Vol. 82, No. 3-4, 14.12.2007, p. 314-320.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review