Numerical Study of Pillar Shapes in Deterministic Lateral Displacement Microfluidic Arrays for Spherical Particle Separation

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

19 Scopus Citations
View graph of relations

Author(s)

  • Jianhui Wei
  • Hui Song
  • Zaiyi Shen
  • Ying He
  • Xianzhi Xu
  • Bing Nan Li

Detail(s)

Original languageEnglish
Article number7111325
Pages (from-to)660-667
Journal / PublicationIEEE Transactions on Nanobioscience
Volume14
Issue number6
Publication statusPublished - 1 Sept 2015
Externally publishedYes

Abstract

Deterministic lateral displacement (DLD) arrays containing shaped pillars have been found to be more effective in biomedical sample separation. This study aims to numerically investigate the interplay between particles and microfluidic arrays, and to find out the key factors in determining the critical size of a DLD device with shaped pillars. A new formula is thus proposed to estimate the critical size for spherical particle separation in this kind of new DLD microfluidic arrays. The simulation results show that both rectangular and I-shaped arrays have considerably smaller critical sizes. The ratio of sub-channel widths is also found to play an important role in reducing the critical sizes. This paves a valuable way toward designing high-performance DLD microfluidic arrays. © 2002-2011 IEEE.

Research Area(s)

  • Deterministic lateral displacement, immersed boundary, lattice Boltzmann method, microfluidic arrays, spherical particle separation

Bibliographic Note

Publication details (e.g. title, author(s), publication statuses and dates) are captured on an “AS IS” and “AS AVAILABLE” basis at the time of record harvesting from the data source. Suggestions for further amendments or supplementary information can be sent to lbscholars@cityu.edu.hk.

Citation Format(s)

Numerical Study of Pillar Shapes in Deterministic Lateral Displacement Microfluidic Arrays for Spherical Particle Separation. / Wei, Jianhui; Song, Hui; Shen, Zaiyi et al.
In: IEEE Transactions on Nanobioscience, Vol. 14, No. 6, 7111325, 01.09.2015, p. 660-667.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review