Novel chiral di-2-pyridyl ketone ligands : Crystal structure of a copper complex and its activity in the copper-catalyzed enantioselective cyclopropanation of styrene

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review

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Author(s)

  • Hoi-Lun Kwong
  • Leung-Shi Cheng
  • Wing-Sze Lee
  • Wing-Leung Wong
  • Wing-Tak Wong

Detail(s)

Original languageEnglish
Pages (from-to)1997-2002
Journal / PublicationEuropean Journal of Inorganic Chemistry
Issue number9
Publication statusPublished - 2000

Abstract

New C2-symmetric chiral di-2-pyridyl ketones were prepared from readily available chiral bromopyridines. Their complexes with copper were synthesized and characterized by X-ray crystallography. The copper complexes were prepared in situ with the triflate anion and were found to be active in the catalysis of cyclopropanation with diazo esters and alkenes. Reaction yields were excellent and enantioselectivities of up to 61% were observed.

Research Area(s)

  • Asymmetric catalysis, Chiral auxiliaries, Copper, Cyclopropanation, Nitrogen heterocycles, Pyridyl

Citation Format(s)

Novel chiral di-2-pyridyl ketone ligands: Crystal structure of a copper complex and its activity in the copper-catalyzed enantioselective cyclopropanation of styrene. / Kwong, Hoi-Lun; Cheng, Leung-Shi; Lee, Wing-Sze et al.
In: European Journal of Inorganic Chemistry, No. 9, 2000, p. 1997-2002.

Research output: Journal Publications and ReviewsRGC 21 - Publication in refereed journalpeer-review