Non-Invasive Capillary Blood Pressure Measurement Enabling Early Detection and Classification of Venous Congestion

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

1 Scopus Citations
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Author(s)

  • Jing Liu
  • Bryan Yan
  • Shih-Chi Chen
  • Charles Sodini
  • Ni Zhao

Related Research Unit(s)

Detail(s)

Original languageEnglish
Pages (from-to)2877-2886
Number of pages10
Journal / PublicationIEEE Journal of Biomedical and Health Informatics
Volume25
Issue number8
Online published29 Jan 2021
Publication statusPublished - Aug 2021

Abstract

Capillary blood pressure (CBP) is the primary driving force for fluid exchange across microvessels. Subclinical systemic venous congestion prior to overt peripheral edema can directly result in elevated peripheral CBP. Therefore, CBP measurements can enable timely edema control in a variety of clinical cases including venous insufficiency, heart failure and so on. However, currently CBP measurements can be only done invasively and with a complicated experimental setup. In this work, we proposed an opto-mechanical system to achieve non-invasive and automatic CBP measurements through modifying the widely implemented oscillometric technique in home-use arterial blood pressure monitors. The proposed CBP system is featured with a blue light photoplethysmography sensor embedded in finger/toe cuffs to probe skin capillary pulsations. The experimental results demonstrated the proposed CBP system can track local CBP changes induced by different levels of venous congestion. Leveraging the decision tree technique, we demonstrate the use of a multi-site CBP measurement at fingertips and toes to classify four categories of subjects (total N = 40) including patients with peripheral arterial disease, varicose veins and heart failure. Our work demonstrates the promising non-invasive CBP measurement as well as its great potential in realizing point-of-care systems for the management of cardiovascular diseases.

Research Area(s)

  • Biomedical measurement, Biomedical monitoring, Blood, capillary blood pressure, Oscillators, oscillometric blood pressure measurement, photoplethysmography, Pressure measurement, Skin, venous congestion, Wavelength measurement

Citation Format(s)

Non-Invasive Capillary Blood Pressure Measurement Enabling Early Detection and Classification of Venous Congestion. / Liu, Jing; Yan, Bryan; Chen, Shih-Chi; Zhang, Yuan-Ting; Sodini, Charles; Zhao, Ni.

In: IEEE Journal of Biomedical and Health Informatics, Vol. 25, No. 8, 08.2021, p. 2877-2886.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review