Non-covalent binding of luminescent transition metal polypyridine complexes to avidin, indole-binding proteins and estrogen receptors

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Keith Hing-Kit Tsang
  • Ka-Shing Sze
  • Chi-Keung Chung
  • Terence Kwok-Ming Lee
  • Kenneth Yin Zhang
  • Wai-Ki Hui
  • Chi-Kwan Li
  • Jason Shing-Yip Lau
  • Dominic Chun-Ming Ng
  • Nianyong Zhu

Detail(s)

Original languageEnglish
Pages (from-to)2292-2310
Journal / PublicationCoordination Chemistry Reviews
Volume251
Issue number17-20
Publication statusPublished - Sep 2007

Abstract

A number of luminescent transition metal complexes possess rich photophysical and photochemical properties that allow them to serve as useful labels and probes for biological molecules. This article describes the current trend in this area of research, with emphasis on our recent work on luminescent rhenium(I), iridium(III) and ruthenium(II) polypyridine complexes as non-covalent probes for avidin, indole-binding proteins and estrogen receptors. We focus on the molecular design, photophysical properties and biomolecule-binding behaviour of these systems; different approaches to enhancing the detection sensitivity are also discussed. © 2006 Elsevier B.V. All rights reserved.

Research Area(s)

  • Avidin, Biological probes, Biotin, Estrogen receptors, Indole-binding proteins, Luminescence

Citation Format(s)

Non-covalent binding of luminescent transition metal polypyridine complexes to avidin, indole-binding proteins and estrogen receptors. / Lo, Kenneth Kam-Wing; Tsang, Keith Hing-Kit; Sze, Ka-Shing; Chung, Chi-Keung; Lee, Terence Kwok-Ming; Zhang, Kenneth Yin; Hui, Wai-Ki; Li, Chi-Kwan; Lau, Jason Shing-Yip; Ng, Dominic Chun-Ming; Zhu, Nianyong.

In: Coordination Chemistry Reviews, Vol. 251, No. 17-20, 09.2007, p. 2292-2310.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review