Nickel release behavior, cytocompatibility, and superelasticity of oxidized porous single-phase NiTi

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review

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Author(s)

  • Shuilin Wu
  • Xiangmei Liu
  • Y. L. Chan
  • J. P Y Ho
  • C. L. Chu
  • K. W K Yeung
  • W. W. Lu
  • K. M C Cheung
  • K. D K Luk

Detail(s)

Original languageEnglish
Pages (from-to)948-955
Journal / PublicationJournal of Biomedical Materials Research - Part A
Volume81
Issue number4
Publication statusPublished - 15 Jun 2007

Abstract

Porous NiTi shape memory alloys are one of the promising biomaterials for surgical implants because of their unique shape memory effects and porous structure with open pores. However, the complex surface morphology and larger area of porous NiTi compared to dense NiTi make it more vulnerable from the viewpoint of release of nickel, which can cause deleterious effects in the human body. It is also more difficult to modify the exposed surfaces of a porous structure using conventional surface modification technologies. In this work, oxidation in conjunction with postreaction heat treatment was used to modify the surfaces of porous single-phase NiTi prepared by capsule-free hot isostatic pressing to mitigate Ni leaching and enhance the surface properties. Differential scanning calorimetry thermal analysis, uniaxial compression tests, inductively-coupled plasma mass spectrometry, and cell cultures reveal that porous NiTi alloys oxidized at 450°C for 1 h have an austenite transition temperature below 37°C, excellent superelasticity, lower nickel release, and no cytotoxicity. © 2007 Wiley Periodicals, Inc.

Research Area(s)

  • Biocompatibility, Nickel release, Oxidation, Porous NiTi, Superelasticity

Citation Format(s)

Nickel release behavior, cytocompatibility, and superelasticity of oxidized porous single-phase NiTi. / Wu, Shuilin; Liu, Xiangmei; Chan, Y. L.; Ho, J. P Y; Chung, C. Y.; Chu, Paul K.; Chu, C. L.; Yeung, K. W K; Lu, W. W.; Cheung, K. M C; Luk, K. D K.

In: Journal of Biomedical Materials Research - Part A, Vol. 81, No. 4, 15.06.2007, p. 948-955.

Research output: Journal Publications and Reviews (RGC: 21, 22, 62)21_Publication in refereed journalpeer-review